ArticleThe Plant cell2004
Silencing of hydroxycinnamoyl-coenzyme A shikimate/quinate hydroxycinnamoyltransferase affects phenylpropanoid biosynthesis.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 238 papers.
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Who cites it
238 citing papers in PubMed, 590 citations in OpenAlex.
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- Long non-coding RNA landscape and ceRNA networks underlying the drought response of Cannabis sativa L.BMC plant biology · 2026Article
- Genome-wide identification of HCT gene family in sugarcane (Saccharum spp. hybrid) and characterization of putative cis-elements in gene regulation.BMC genomics · 2026Article
- Study on biosynthesis pathway and accumulation mechanism of the dihydrochalcones inHorticulture research · 2026Article
- Article
- Advances in the Function Roles of Hydroxycinnamoyl-CoA Shikimate/Quinate Hydroxycinnamoyl Transferases: A Key Enzyme Linking Phenylpropanoid Metabolism to Plant Terrestrial Adaptation.Plants (Basel, Switzerland) · 2026Review
- Cloning and Characterization ofGenes · 2026Article
- Integrative analysis of the metabolome and transcriptome reveals the mechanism of flower color and antioxidant capacity in threeFrontiers in plant science · 2026Article
- An examination of the quinic acid utilization genes in Aspergillus niger reveals the involvement of 2 pH-dependent permeases.G3 (Bethesda, Md.) · 2025Article
- Mechanistic insights into the delayed yellowing of broccoli by the combination of ectoine and lactide peptide.NPJ science of food · 2025Article
- Molecular Mechanisms and Crosstalk Signaling in Soybean's Response to Water Deficit and Excess: Implications for Stress Resilience and Productivity.Plants (Basel, Switzerland) · 2025Article
- Integrative Comparison of Variations in Taste, Aroma, and Sensory Characteristics Among Four Sweet Cherry Cultivars to Explore Quality Differences During Storage.Foods (Basel, Switzerland) · 2025Article
- A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis.Plant, cell & environment · 2025Article
- Exploring the Cytokinin Profile ofMetabolites · 2025Article
- Understanding genetic architecture overcomes tradeoffs between seed quality and insect resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Modulation of lignin and anthocyanin homeostasis by GTP cyclohydrolase1 in maize.Plant biotechnology journal · 2025Article
- Proteome Reprogramming and Acquired Stress Tolerance in Potato Cells Exposed to Acute or Stepwise Water Deficit.Plant, cell & environment · 2025Article
178 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hydroxyl group in the 3-position of the phenylpropanoid compounds is introduced at the level of coumarate shikimate/quinate esters, whose synthesis implicates an acyltransferase activity. Specific antibodies raised against the recombinant tobacco (Nicotiana tabacum) acyltransferase revealed the accumulation of the enzyme in stem vascular tissues of tobacco, in accordance with a putative role in lignification. For functional analysis, the acyltransferase gene was silenced in Arabidopsis thaliana and N. benthamiana by RNA-mediated posttranscriptional gene silencing. In Arabidopsis, gene silencing resulted in a dwarf phenotype and changes in lignin composition as indicated by histochemical staining. An in-depth study of silenced N. benthamiana plants by immunological, histochemical, and chemical methods revealed the impact of acyltransferase silencing on soluble phenylpropanoids and lignin content and composition. In particular, a decrease in syringyl units and an increase in p-hydroxyphenyl units were recorded. Enzyme immunolocalization by confocal microscopy showed a correlation between enzyme accumulation levels and lignin composition in vascular cells. These results demonstrate the function of the acyltransferase in phenylpropanoid biosynthesis.
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