ArticlePlant molecular biology2004
KNAT6 gene of Arabidopsis is expressed in roots and is required for correct lateral root formation.
Article in Plant molecular biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Genome-wide identification and expression profile analysis of TALE superfamily genes under hormone and abiotic stress in maize (Frontiers in plant science · 2025Article
- BREVIPEDICELLUS Positively Regulates Salt-Stress Tolerance inInternational journal of molecular sciences · 2023Article
- Genome-wide identification of the KNOTTED HOMEOBOX gene family and their involvement in stalk development in flowering Chinese cabbage.Frontiers in plant science · 2022Article
- LATERAL ORGAN BOUNDARIES DOMAIN 25 functions as a key regulator of haustorium development in dodders.Plant physiology · 2021Article
- Protocol for screening and expression studies of T-DNA and tagging-based insertional3 Biotech · 2021Article
- Targeted mutation of transcription factor genes alters metaxylem vessel size and number in rice roots.Plant direct · 2021Article
- Evolutionary Relationships and Divergence of KNOTTED1-Like Family Genes Involved in Salt Tolerance and Development in Cotton (Frontiers in plant science · 2021Article
- Article
- Identification of BELL Transcription Factors Involved in Nodule Initiation and Development in the LegumesPlants (Basel, Switzerland) · 2020Article
- The LATERAL ROOT DENSITY gene regulates root growth during water stress in wheat.Plant biotechnology journal · 2020Article
- Reprogramming of the Developmental Program ofFrontiers in plant science · 2020Article
- Transcriptomic and Metabolomic Reprogramming from Roots to Haustoria in the Parasitic Plant, Thesium chinense.Plant & cell physiology · 2018Article
- Conservation of polypyrimidine tract binding proteins and their putative target RNAs in several storage root crops.BMC genomics · 2018Article
- Article
- Transcriptional, posttranscriptional, and posttranslational regulation of SHOOT MERISTEMLESS gene expression in Arabidopsis determines gene function in the shoot apex.Plant physiology · 2015Article
- Strategies for improving potassium use efficiency in plants.Molecules and cells · 2014Review
- Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.Plant physiology · 2014Article
- Systems approaches to study root architecture dynamics.Frontiers in plant science · 2013Review
- KNOX1 is expressed and epigenetically regulated during in vitro conditions in Agave spp.BMC plant biology · 2012Article
- Antagonistic interaction of BLADE-ON-PETIOLE1 and 2 with BREVIPEDICELLUS and PENNYWISE regulates Arabidopsis inflorescence architecture.Plant physiology · 2012Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As part of a programme to determine whether root development requires a pathway involving KNOTTED-like homeobox ( KNOX ) genes, we cloned the KNAT6 cDNA, a member of the KNOX gene family in Arabidopsis, from root tissue. The KNAT6 cDNA is represented by two isoforms, suggesting that the KNAT6 transcript is subject to alternative splicing. Promoter-reporter and RT-PCR analysis confirms expression of the KNAT6 gene in roots, and in particular in the phloem tissue close to the site of lateral root initiation, though not in the primary or lateral root meristem. The KNAT6 gene promoter activity is altered in pattern by treatment with exogenous auxin and in the rooty mutant background, with expression shifting distally in the root. In contrast, exogenous cytokinin suppresses KNAT6 promoter activity. KNAT6::GFP fusion protein is localized to the nucleus, consistent with the predicted function of KNAT6 as a transcription factor. Over-expression of the more abundant shorter isoform of the KNAT6 cDNA, but not of the less abundant longer form, leads to a lobed leaf phenotype, but no consistently aberrant root phenotype. Down-regulation of KNAT6 expression by RNA interference was associated with an increased total number of lateral roots. These data indicate a role for KNAT6 in modulating lateral root formation.
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