ArticleInternational archives of occupational and environmental health2004
Silica, silicosis and lung-cancer: results from a cohort study in the stone and quarry industry.
Article in International archives of occupational and environmental health, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Occupational exposure to silica and risk of gastrointestinal cancers: a systematic review and meta-analysis of cohort studies.International archives of occupational and environmental health · 2024Pooled it
- Occupational exposure to silica dust and risk of lung cancer: an updated meta-analysis of epidemiological studies.BMC public health · 2016Pooled it
- Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health question.International archives of occupational and environmental health · 2009Pooled it
- Peak Inhalation Exposure Metrics Used in Occupational Epidemiologic and Exposure Studies.Frontiers in public health · 2020Review
- Silicosis and lung cancer: current perspectives.Lung Cancer (Auckland, N.Z.) · 2018Review
- High Cigarette and Poly-Tobacco Use Among Workers in a Dusty Industry: New Jersey Quarry Workers.Journal of occupational and environmental medicine · 2016Article
- Determination of Crystalline Silica in Dust at Low Concentrations by Low-Temperature Infrared Spectrometry.Annual book of ASTM standards. Section 11, Water and environmental technology. ASTM Committee E-35 on Pesticides · 2013Article
- Performance of high flow rate samplers for respirable particle collection.The Annals of occupational hygiene · 2010Article
- Mortality from non-malignant respiratory diseases among people with silicosis in Hong Kong: exposure-response analyses for exposure to silica dust.Occupational and environmental medicine · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWorkers compensated for silicosis outside the mining industry are at an increased risk of developing lung cancer. In the meta-analyses no data from Germany are involved. Furthermore, exposure data are necessary if a threshold value is to be assessed in order to reduce the risk for silicosis and also for lung cancer.
methodA cohort study among workers compensated for silicosis between 1988 and 2000 from the stone and quarry industry in Germany has been initiated. The cohort was followed up until the end of 2001. From all workers a detailed description of their jobs was assessed.
resultsFour hundred and forty workers were enrolled in the study. During the follow-up 144 workers died, compared with 74.35 expected cases based on the mortality rates of the general population from Germany, leading to a standard mortality ratio (SMR) of 1.94 (95% CI 1.63-2.28). Lung cancer was the cause of death in 16 cases (SMR 2.40; 95% CI 1.37-3.90). All workers had a peak exposure above 0.15 mg/m3, the current threshold value. The cumulative exposure was above 2 mg/m3.years and the average exposure was 0.10 mg/m3 or larger. No association between the exposure and the risk of developing lung cancer could be observed.
conclusionsWorkers from the stone and quarry industry compensated for silicosis are at an increased risk of developing lung cancer. In order to reduce that risk, the exposure has to be lowered, with a peak exposure below 0.15 mg/m3 and an average exposure below 0.10 mg/m3.
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