ArticleThe Plant cell2004
The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
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Who cites it
86 citing papers in PubMed, 179 citations in OpenAlex.
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- FIMBRIN2 Regulates ABA-Induced Stomatal Closure by Promoting Microfilament Bundling and Turnover in Arabidopsis Guard Cells.Plant direct · 2026Article
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- The epidermis coordinates multi-scale symmetry breaking in chiral root growth.Nature communications · 2025Article
- On the mechanical origins of waving, coiling and skewing inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Comparative Transcriptomic and Metabolomic Analyses of Differences in Trunk Spiral Grain inInternational journal of molecular sciences · 2023Article
- PHYTOCHROME INTERACTING FACTOR 4 regulates microtubule organization to mediate high temperature-induced hypocotyl elongation in Arabidopsis.The Plant cell · 2023Article
- Genome-Wide Identification, Characterization, and Expression Analysis ofInternational journal of molecular sciences · 2023Article
- The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis.The Plant cell · 2023Article
- Defects in division plane positioning in the root meristematic zone affect cell organization in the differentiation zone.Journal of cell science · 2022Article
- Plant Gravitropism: From Mechanistic Insights into Plant Function on Earth to Plants Colonizing Other Worlds.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Rice microtubule-associated protein OsMAP65-3.1, but not OsMAP65-3.2, plays a critical role in phragmoplast microtubule organization in cytokinesis.Frontiers in plant science · 2022Article
- Article
- Discovery, characterization and functional improvement of kumamonamide as a novel plant growth inhibitor that disturbs plant microtubules.Scientific reports · 2021Article
- The loss of function of HEL, which encodes a cellulose synthase interactive protein, causes helical and vine-like growth of tomato.Horticulture research · 2020Article
- Nitrate deficiency induces differential endocytosis in roots through NRT1.1.Plant signaling & behavior · 2020Article
- Recurrent requirement for the mDevelopment (Cambridge, England) · 2020Article
- A simple, non-toxic method for separating seeds based on density, and its application in isolatingApplications in plant sciences · 2020Article
- NRT1.1-Mediated Nitrate Suppression of Root Coiling Relies on PIN2- and AUX1-Mediated Auxin Transport.Frontiers in plant science · 2020Article
- Root Skewing-Associated Genes Impact the Spaceflight Response ofFrontiers in plant science · 2020Article
26 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
The sku6-1 mutant of Arabidopsis thaliana exhibits altered patterns of root and organ growth. sku6 roots, etiolated hypocotyls, and leaf petioles exhibit right-handed axial twisting, and root growth on inclined agar media is strongly right skewed. The touch-dependent sku6 root skewing phenotype is suppressed by the antimicrotubule drugs propyzamide and oryzalin, and right skewing is exacerbated by cold treatment. Cloning revealed that sku6-1 is allelic to spiral1-1 (spr1-1). However, modifiers in the Columbia (Col) and Landsberg erecta (Ler) ecotype backgrounds mask noncomplementation in sku6-1 (Col)/spr1-1 (Ler) F1 plants. The SPR1 gene encodes a plant-specific 12-kD protein that is ubiquitously expressed and belongs to a six-member gene family in Arabidopsis. An SPR1:green fluorescent protein (GFP) fusion expressed in transgenic seedlings localized to microtubules within the cortical array, preprophase band, phragmoplast, and mitotic spindle. SPR1:GFP was concentrated at the growing ends of cortical microtubules and was dependent on polymer growth state; the microtubule-related fluorescence dissipated upon polymer shortening. The protein has a repeated motif at both ends, separated by a predicted rod-like domain, suggesting that it may act as an intermolecular linker. These observations suggest that SPR1 is involved in microtubule polymerization dynamics and/or guidance, which in turn influences touch-induced directional cell expansion and axial twisting.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.