ArticleNucleic acids research2004
Microfluidic device reads up to four consecutive base pairs in DNA sequencing-by-synthesis.
Article in Nucleic acids research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology.Chemical reviews · 2021Review
- Microfluidics for Artificial Life: Techniques for Bottom-Up Synthetic Biology.Micromachines · 2019Review
- Microfluidics-Based Chromosome Conformation Capture (3C) Technology for Examining Chromatin Organization with a Low Quantity of Cells.Analytical chemistry · 2018Article
- Patterning of supported gold monolayers via chemical lift-off lithography.Beilstein journal of nanotechnology · 2017Article
- New tools and new biology: recent miniaturized systems for molecular and cellular biology.Molecules and cells · 2013Review
- Transposases are the most abundant, most ubiquitous genes in nature.Nucleic acids research · 2010Review
- RNA-protein binding kinetics in an automated microfluidic reactor.Nucleic acids research · 2009Article
- Opportunities for microfluidic technologies in synthetic biology.Journal of the Royal Society, Interface · 2009Review
- DNA hybridization sensor based on aurothiomalate electroactive label on glassy carbon electrodes.Biosensors & bioelectronics · 2007Article
- Miniaturized PCR chips for nucleic acid amplification and analysis: latest advances and future trends.Nucleic acids research · 2007Review
- Experimentally validated quantitative linear model for the device physics of elastomeric microfluidic valves.Journal of applied physics · 2007Article
- Microfluidic vias enable nested bioarrays and autoregulatory devices in Newtonian fluids.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- An analysis of the feasibility of short read sequencing.Nucleic acids research · 2005Article
- Miniaturized detection technology in molecular diagnostics.Expert review of molecular diagnostics · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
We have developed the first fully integrated microfluidic system for DNA sequencing-by-synthesis. Using this chip and fluorescence detection, we have reliably sequenced up to 4 consecutive bps. The described sequencer can be integrated with other microfluidic components on the same chip to produce true lab-on-a-chip technology. The surface chemistry that was designed to anchor the DNA to elastomeric microchannels is useful in a broad range of studies and applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.