ArticleInfection and immunity2004
Role of Streptococcus pyogenes two-component response regulators in the temporal control of Mga and the Mga-regulated virulence gene emm.
Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Proteomic Characterization of Virulence Factors and Related Proteins inInternational journal of molecular sciences · 2022Article
- Proteomic Characterization of Antibiotic Resistance inInternational journal of molecular sciences · 2021Article
- Proteomic Characterization of Antibiotic Resistance, and Production of Antimicrobial and Virulence Factors inAntibiotics (Basel, Switzerland) · 2020Article
- Regulatory gene mutation: a driving force behind group a Streptococcus strain- and serotype-specific variation.Molecular microbiology · 2017Review
- The fruRBA Operon Is Necessary for Group A Streptococcal Growth in Fructose and for Resistance to Neutrophil Killing during Growth in Whole Human Blood.Infection and immunity · 2016Article
- The small regulatory RNA FasX enhances group A Streptococcus virulence and inhibits pilus expression via serotype-specific targets.Molecular microbiology · 2015Article
- covR Mediated Antibiofilm Activity of 3-Furancarboxaldehyde Increases the Virulence of Group A Streptococcus.PloS one · 2015Article
- Natural disruption of two regulatory networks in serotype M3 group A Streptococcus isolates contributes to the virulence factor profile of this hypervirulent serotype.Infection and immunity · 2014Article
- Identification of cold-temperature-regulated genes in Flavobacterium psychrophilum.Applied and environmental microbiology · 2011Article
- Article
- A decade of molecular pathogenomic analysis of group A Streptococcus.The Journal of clinical investigation · 2009Review
- TrxR, a new CovR-repressed response regulator that activates the Mga virulence regulon in group A Streptococcus.Infection and immunity · 2008Article
- CcpA-mediated repression of streptolysin S expression and virulence in the group A streptococcus.Infection and immunity · 2008Article
- Defects in ex vivo and in vivo growth and sensitivity to osmotic stress of group A Streptococcus caused by interruption of response regulator gene vicR.Microbiology (Reading, England) · 2006Article
- Expression microarray and mouse virulence analysis of four conserved two-component gene regulatory systems in group a streptococcus.Infection and immunity · 2006Article
- Growth characteristics of and virulence factor production by group A Streptococcus during cultivation in human saliva.Infection and immunity · 2005Article
- Evolution of transcription regulatory genes is linked to niche specialization in the bacterial pathogen Streptococcus pyogenes.Journal of bacteriology · 2005Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We examined the role of Streptococcus pyogenes two-component response regulators (SptR) in expression of Mga and the Mga-regulated gene emm. Both serotype M6 and serotype M1 mutants in 12 of the 13 identified sptR genes exhibited levels of emm transcripts and Mga protein comparable to those of the wild type during exponential and stationary phases of growth. Thus, temporal control of these virulence genes does not require Spt response regulators.
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