ArticleCritical care (London, England)2004
Hyperglycaemic index as a tool to assess glucose control: a retrospective study.
Article in Critical care (London, England), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ingredients for adequate evaluation of blood glucose algorithms as applied to the critically ill.Critical care (London, England) · 2009Pooled it
- A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset.Critical care (London, England) · 2008Pooled it
- Effect of high-dose dexamethasone on perioperative lactate levels and glucose control: a randomized controlled trial.Critical care (London, England) · 2015Trial
- LOGIC-insulin algorithm-guided versus nurse-directed blood glucose control during critical illness: the LOGIC-1 single-center, randomized, controlled clinical trial.Diabetes care · 2013Trial
- A stepwise approach toward closed-loop blood glucose control for intensive care unit patients: results from a feasibility study in type 1 diabetic subjects using vascular microdialysis with infrared spectrometry and a model predictive control algorithm.Journal of diabetes science and technology · 2011Trial
- A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study.Intensive care medicine · 2009Trial
- Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care.Intensive care medicine · 2009Trial
- Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients.Intensive care medicine · 2008Trial
- Early versus late intravenous insulin administration in critically ill patients.Intensive care medicine · 2008Trial
- The impact of a reduced dose of dexamethasone on glucose control after coronary artery bypass surgery.Cardiovascular diabetology · 2007Trial
- Stress hyperglycemia ratio is a risk factor for mortality in trauma and surgical intensive care patients: a retrospective cohort study from the MIMIC-IV.European journal of medical research · 2024Article
- An open source tool to compute measures of inpatient glycemic control: translating from healthcare analytics research to clinical quality improvement.JAMIA open · 2021Article
- Evaluating the effectiveness of a multi-faceted inpatient diabetes management program among hospitalised patients with diabetes mellitus.Clinical diabetes and endocrinology · 2020Article
- Impact of post-procedural glycemic variability on cardiovascular morbidity and mortality after transcatheter aortic valve implantation: a post hoc cohort analysis.Cardiovascular diabetology · 2019Observational
- Stress-Induced and Diabetic Hyperglycemia Associated with Higher Mortality among Intensive Care Unit Trauma Patients: Cross-Sectional Analysis of the Propensity Score-Matched Population.International journal of environmental research and public health · 2018Article
- Association of various glycemic variability indices and vascular outcomes in type-2 diabetes patients: A retrospective study.Medicine · 2018Observational
- Mortality Rate Associated with Admission Hyperglycemia in Traumatic Femoral Fracture Patients Is Greater Than Non-Diabetic Normoglycemic Patients but Not Diabetic Normoglycemic Patients.International journal of environmental research and public health · 2017Article
- Comparative Simulation Study of Glucose Control Methods Designed for Use in the Intensive Care Unit Setting via a Novel Controller Scoring Metric.Journal of diabetes science and technology · 2017Article
- Higher Mortality in Trauma Patients Is Associated with Stress-Induced Hyperglycemia, but Not Diabetic Hyperglycemia: A Cross-Sectional Analysis Based on a Propensity-Score Matching Approach.International journal of environmental research and public health · 2017Article
- Prognostic impact of hyperglycemia at onset of methicillin-sensitive Staphylococcus aureus bacteraemia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCritically ill patients may benefit from strict glucose control. An objective measure of hyperglycaemia for assessing glucose control in acutely ill patients should reflect the magnitude and duration of hyperglycaemia, should be independent of the number of measurements, and should not be falsely lowered by hypoglycaemic values. The time average of glucose values above the normal range meets these requirements.
methodsA retrospective, single-centre study was performed at a 12-bed surgical intensive care unit. From 1990 through 2001 all patients over 15 years, staying at least 4 days, were included. Admission type, sex, age, Acute Physiology and Chronic Health Evaluation II score and outcome were recorded. The hyperglycaemic index (HGI) was defined as the area under the curve above the upper limit of normal (glucose level 6.0 mmol/l) divided by the total length of stay. HGI, admission glucose, mean morning glucose, mean glucose and maximal glucose were calculated for each patient. The relations between these measures and 30-day mortality were determined.
resultsIn 1779 patients with a median stay in the intensive care unit of 10 days, the 30-day mortality was 17%. A total of 65,528 glucose values were analyzed. Median HGI was 0.9 mmol/l (interquartile range 0.3-2.1 mmol/l) in survivors versus 1.8 mmol/l (interquartile range 0.7-3.4 mmol/l) in nonsurvivors (P < 0.001). The area under the receiver operator characteristic curve was 0.64 for HGI, as compared with 0.61 and 0.62 for mean morning glucose and mean glucose. HGI was the only significant glucose measure in binary logistic regression.
conclusionHGI exhibited a better relation with outcome than other glucose indices. HGI is a useful measure of glucose control in critically ill patients.
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