Evidence map›Paper›PMID 15151791›Full record

Trial reportAtencion primaria2004

[Efficacy of an intervention to improve treatment compliance in hyperlipidemias].

E Márquez Contreras, J J Casado Martínez, Y Corchado Albalat, R Chaves González, A Grandío, C Losada Velasco, J Obando, J M de Eugenio, J M Barrera

Registry-linked trialOpen access · greenAbstract readClinical TrialComparative StudyEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Atencion primaria, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02314663 (Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With Hypercholesterolaemia), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02314663 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With Hypercholesterolaemia: a Randomised Clinical Trial

TypeinterventionalSponsorGerencia de Atención Primaria, AlbaceteRan2013 to 2015Enrolled358ConditionsHypercholesterolemia, Medication Adherence, Primary Health CareArms"COMBINED STRATEGY"
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Interventions to improve adherence to lipid-lowering medication.The Cochrane database of systematic reviews · 2016
    Pooled it
  2. Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

E Márquez ContrerasMedicina Familiar y Comunitaria, Centro de Salud la Orden, Avda. Italia 107, 5.o A. 21003 Huelva, Spain. emarquezc@papps.org
J J Casado Martínez
Y Corchado Albalat
R Chaves González
A Grandío
C Losada Velasco
J Obando
J M de Eugenio
J M Barrera
Sociedad Andaluza de Medicina Familiar y Comunitaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyse the efficacy of the intervention through a telephone call about patients' compliance with lipaemia therapy.

designControlled, randomised clinical trial.

settingTen clinics at 6 primary care centres.

participants126 people diagnosed with hypercholesterolaemia according to Spanish Consensus criteria were chosen.

interventionTwo groups were formed. The control group (CG) of 63 patients, who received the doctor's normal treatment; and the Intervention group (IG) of 63 patients, who received in addition a telephone call at 2 weeks, 2 months and 4 months. MAIN MEASUREMENTS: Pills were counted and cholesterol, triglycerides, HDL-C and LDL-C determined at the start, and at the third and sixth months. Percentages of patients complying (80%-110%), the mean compliance percentage and the degree of control were compared. The reduction of absolute and relative risk (RAR and RRR) and the mean number of people that required an intervention in order to avoid non-compliance (NI) were calculated.

results115 people (91.26%) completed the survey, 56 in the IG and 59 in the CG. 77.1% complied with the therapy (CI, 68.4-85.8), (CG=64.4%, CI, 55.3-73.5; IG=93.5%, CI, 88.8-98 [P<.001]). Mean compliance ran at 88.7 +/- 10.2 overall, at 84.4 +/- 12.8 in the CG and at 93 +/- 8.2 in the IG (P<.001). The RAR was 29.1%, the RRR 81%, and the NI was 3.43 patients. The patients controlled ran at 43.9% in the IG (CI, 34.9-52.9) and 23.1% in the CG (CI, 15.4-30.8) (P<.005).

conclusionsThe telephone intervention is an efficacious way of improving the percentage of patients complying with lipaemia treatment.

Indexed as

Patient ComplianceCase-Control StudiesCholesterolCholesterol, HDLCholesterol, LDLFemaleHumansHypercholesterolemiaHypolipidemic AgentsMaleMiddle AgedTelephoneTreatment OutcomeTriglyceridesCholesterolCholesterol, HDLCholesterol, LDLHypolipidemic AgentsTriglycerides

Identifiers

PMID15151791
PMCPMC7681830
OpenAlexW2020396168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.