ArticleBritish journal of cancer2004
Cytomegalovirus, Epstein-Barr virus and risk of breast cancer before age 40 years: a case-control study.
Article in British journal of cancer, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cytomegalovirus and Epstein-Barr virus in breast cancer.PloS one · 2015Pooled it
- Detection of Human CytomegalovirusThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2026Article
- Beyond the Usual Suspects: Emerging Associations Between Epstein-Barr Virus Infection/Infectious Mononucleosis and Cancers.Reviews in medical virology · 2026Review
- Cytokine levels in breast cancer are highly dependent on cytomegalovirus (CMV) status.Breast cancer research and treatment · 2024Article
- Human cytomegalovirus alters immune cell profile with potential implications for patient survival in head and neck cancer.Carcinogenesis · 2022Article
- Human Cytomegalovirus Seropositivity and Viral DNA in Breast Tumors Are Associated with Poor Patient Prognosis.Cancers · 2022Article
- Molecular and Serological Prevalence of HCMV in Iranian Patients with Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Productive Infection of Human Breast Cancer Cell Lines with Human Cytomegalovirus (HCMV).Pathogens (Basel, Switzerland) · 2021Article
- Common Childhood Viruses and Pubertal Timing: The LEGACY Girls Study.American journal of epidemiology · 2021Article
- Detection of human papillomavirus genotypes, herpes simplex, varicella zoster and cytomegalovirus in breast cancer patients.Virology journal · 2021Article
- Breast cancer and cytomegalovirus.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020Review
- Human Cytomegalovirus DNA among Women with Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2019Article
- Human cytomegalovirus interleukin-10 enhances matrigel invasion of MDA-MB-231 breast cancer cells.Cancer cell international · 2017Article
- Evaluation of human cytomegalovirus antigen expression in invasive breast carcinoma in a population of Iranian patients.Infectious agents and cancer · 2017Article
- Does Regular Exercise Counter T Cell Immunosenescence Reducing the Risk of Developing Cancer and Promoting Successful Treatment of Malignancies?Oxidative medicine and cellular longevity · 2017Review
- Donor Characteristics of Pancreas Transplantation in Australia and New Zealand: A Cohort Study 1984-2014.Transplantation direct · 2016Article
- Human cytomegalovirus infection enhances NF-κB/p65 signaling in inflammatory breast cancer patients.PloS one · 2013Article
- An expanded myeloid derived suppressor cell population does not play a role in gammaherpesvirus-exacerbated breast cancer metastases.Infectious agents and cancer · 2012Article
- Exacerbated metastatic disease in a mouse mammary tumor model following latent gammaherpesvirus infection.Infectious agents and cancer · 2012Article
- Association between chronic viral hepatitis infection and breast cancer risk: a nationwide population-based case-control study.BMC cancer · 2011Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated whether there is an association between cytomegalovirus (CMV) and Epstein-Barr virus (EBV) IgG levels and risk of breast cancer before age 40 years. CMV and EBV IgG levels were measured in stored plasma from 208 women with breast cancer and 169 controls who participated in the Australian Breast Cancer Family Study (ABCFS), a population-based case-control study. CMV and EBV IgG values were measured in units of optical density (OD). Cases and controls did not differ in seropositivity for CMV (59 and 57% respectively; P=0.8) or EBV (97 and 96% respectively; P=0.7). In seropositive women, mean IgG values were higher in cases than controls for CMV (1.20 vs 0.98 OD, P=0.005) but not for EBV (2.65 vs 2.57 OD, P=0.5). The adjusted odds ratios per OD unit were 1.46 (95% CI 1.06-2.03) for CMV IgG and 1.11 (0.93-1.33) for EBV IgG. The higher mean CMV IgG levels found in women with breast cancer could be the result of a more recent infection with CMV, and may mean that late exposure to CMV is a risk factor for breast cancer.
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