Evidence map›Paper›PMID 15150216›Full record

ArticleJournal of bacteriology2004

Circularized chromosome with a large palindromic structure in Streptomyces griseus mutants.

Tetsuya Uchida, Naoto Ishihara, Hiroyuki Zenitani, Keiichiro Hiratsu, Haruyasu Kinashi

Abstract read
In one paragraph

Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Genetics of Streptomyces rimosus, the oxytetracycline producer.Microbiology and molecular biology reviews : MMBR · 2006
    Review
  3. The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution.Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tetsuya UchidaDepartment of Molecular Biotechnology, Hiroshima University, Higashi-Hiroshima 739-8530, Japan.
Naoto Ishihara
Hiroyuki Zenitani
Keiichiro Hiratsu
Haruyasu Kinashi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptomyces linear chromosomes display various types of rearrangements after telomere deletion, including circularization, arm replacement, and amplification. We analyzed the new chromosomal deletion mutants Streptomyces griseus 301-22-L and 301-22-M. In these mutants, chromosomal arm replacement resulted in long terminal inverted repeats (TIRs) at both ends; different sizes were deleted again and recombined inside the TIRs, resulting in a circular chromosome with an extremely large palindrome. Short palindromic sequences were found in parent strain 2247, and these sequences might have played a role in the formation of this unique structure. Dynamic structural changes of Streptomyces linear chromosomes shown by this and previous studies revealed extraordinary strategies of members of this genus to keep a functional chromosome, even if it is linear or circular.

Indexed as

Chromosomes, BacterialAmino Acid SequenceBase SequenceChromosome DeletionGene AmplificationMolecular Sequence DataMutationStreptomyces griseusTerminal Repeat Sequences

Identifiers

PMID15150216
PMCPMC415753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.