ArticleJournal of molecular biology2004
Identification of a new antizyme mRNA +1 frameshifting stimulatory pseudoknot in a subset of diverse invertebrates and its apparent absence in intermediate species.
Article in Journal of molecular biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Biological Significance and Therapeutic Promise of Programmed Ribosomal Frameshifting.International journal of molecular sciences · 2025Review
- Absolute quantification of translational regulation and burden using combined sequencing approaches.Molecular systems biology · 2019Article
- Roles of polyamines in translation.The Journal of biological chemistry · 2018Review
- ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?Biology direct · 2017Article
- A reconstituted cell-free assay for the evaluation of the intrinsic activity of purified human ribosomes.Nature protocols · 2016Article
- A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA.The Journal of biological chemistry · 2015Article
- Involvement of Antizyme Characterized from the Small Abalone Haliotis diversicolor in Gonadal Development.PloS one · 2015Article
- NMR-assisted prediction of RNA secondary structure: identification of a probable pseudoknot in the coding region of an R2 retrotransposon.Journal of the American Chemical Society · 2008Article
- The major form of hepatitis C virus alternate reading frame protein is suppressed by core protein expression.Nucleic acids research · 2008Article
- FSDB: a frameshift signal database.Computational biology and chemistry · 2007Article
- Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation.Nucleic acids research · 2007Review
- Specific effects of ribosome-tethered molecular chaperones on programmed -1 ribosomal frameshifting.Eukaryotic cell · 2006Article
- Evolutionary specialization of recoding: frameshifting in the expression of S. cerevisiae antizyme mRNA is via an atypical antizyme shift site but is still +1.RNA (New York, N.Y.) · 2006Article
- Antisense-induced ribosomal frameshifting.Nucleic acids research · 2006Article
- Article
- Novel application of sRNA: stimulation of ribosomal frameshifting.RNA (New York, N.Y.) · 2004Article
- Predicting genes expressed via -1 and +1 frameshifts.Nucleic acids research · 2004Article
- Mechanisms and implications of programmed translational frameshifting.Wiley interdisciplinary reviews. RNAReview
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The expression of eukaryotic antizyme genes requires +1 translational frameshifting. The frameshift in decoding most vertebrate antizyme mRNAs is stimulated by an RNA pseudoknot 3' of the frameshift site. Although the frameshifting event itself is conserved in a wide variety of organisms from yeast to mammals, until recently no corresponding 3' RNA pseudoknot was known in invertebrate antizyme mRNAs. A pseudoknot, different in structure and origin from its vertebrate counterparts, is now shown to be encoded by the antizyme genes of distantly related invertebrates. Identification of the 3' frameshifting stimulator in intermediate species or other invertebrates remains unresolved.
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Registered trials
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