ArticleClinical and experimental immunology2004
Decrease of CD154 intensity on peripheral CD4+ T cells in autoimmune thyroid disease.
Article in Clinical and experimental immunology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 11 citations in OpenAlex.
- PD-L1 Inhibits T Cell-Induced Cytokines and Hyaluronan ExpressionFrontiers in immunology · 2022Article
- Stimulation-dependent induction of CD154 on a subset of CD4+ FoxP3+ T-regulatory cells.International immunopharmacology · 2011Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
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Abstract
To clarify immunological differences among patients with Graves' disease (GD) and Hashimoto's disease (HD) at various levels of severity, we examined the expression of the CD154 molecules on peripheral T cells, which regulate B cell activation, B cell differentiation, and T-cell survival. We found decreases in the intensities of CD154 on peripheral CD4(+) cells from euthyroid patients with GD and HD, but we did not find any differences between patients with different disease severities. CD8(+) cells did not express CD154 molecules. Thus, CD154 expression on CD4(+) cells may be related to the pathogenesis of the autoimmune thyroid diseases, not to the disease severity.
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