ArticleExperimental brain research2004
Modulation of motor unit discharge rate and H-reflex amplitude during submaximal fatigue of the human soleus muscle.
Article in Experimental brain research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Passive Stretching and Explosive Jumps Acutely Reduce Spinal Reflex Excitability and Alter Sit-To-Stand Biomechanics in Active Adults.Journal of musculoskeletal & neuronal interactions · 2026Trial
- Increased spinal excitability does not offset central activation failure.Experimental brain research · 2006Trial
- The Hoffmann Reflex.NeuroSci · 2026Review
- Effects of neuromuscular electrical stimulation on neuromuscular function and muscle quality in patient following anterior cruciate ligament reconstruction.Journal of exercise rehabilitation · 2025Article
- Acute adaptation of central and peripheral motor unit features to exercise-induced fatigue differs with concentric and eccentric loading.Experimental physiology · 2023Article
- Impaired Firing Behavior of Individually Tracked Paretic Motor Units During Fatiguing Contractions of the Dorsiflexors and Functional Implications Post Stroke.Frontiers in neurology · 2020Article
- Sex difference in fatigability of knee extensor muscles during sustained low-level contractions.Scientific reports · 2019Article
- Determinants, analysis and interpretation of the muscle compound action potential (M wave) in humans: implications for the study of muscle fatigue.European journal of applied physiology · 2018Review
- Effect of Task Failure on Intermuscular Coherence Measures in Synergistic Muscles.Applied bionics and biomechanics · 2018Article
- A motor unit-based model of muscle fatigue.PLoS computational biology · 2017Article
- Variability in spatio-temporal pattern of trapezius activity and coordination of hand-arm muscles during a sustained repetitive dynamic task.Experimental brain research · 2017Article
- Spinal Cord Excitability and Sprint Performance Are Enhanced by Sensory Stimulation During Cycling.Frontiers in human neuroscience · 2017Article
- Modulation of exercise-induced spinal loop properties in response to oxygen availability.European journal of applied physiology · 2015Article
- Stressor-induced increase in muscle fatigability of young men and women is predicted by strength but not voluntary activation.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Article
- Neural control of muscle force: indications from a simulation model.Journal of neurophysiology · 2013Article
- Influence of proprioceptive feedback on the firing rate and recruitment of motoneurons.Journal of neural engineering · 2012Article
- Muscle fatigue: from observations in humans to underlying mechanisms studied in intact single muscle fibres.European journal of applied physiology · 2010Review
- Modulation in voluntary neural drive in relation to muscle soreness.European journal of applied physiology · 2008Article
- Low-frequency common modulation of soleus motor unit discharge is enhanced during postural control in humans.Experimental brain research · 2006Article
- The effect of sustained low-intensity contractions on supraspinal fatigue in human elbow flexor muscles.The Journal of physiology · 2006Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Declining motor unit discharge rates and H-reflex amplitude have been observed in separate experiments during fatiguing submaximal contractions in humans. The purpose of this experiment was to investigate motor unit discharge rate, H-reflex amplitude, and twitch contractile properties concurrently during a fatiguing submaximal isometric contraction of the ankle plantarflexors. Eleven healthy subjects performed fatiguing contractions of low force (25% maximal voluntary contraction (MVC)) or high force (42-66% MVC). Hoffmann (H)-reflexes, muscle compound action potentials (M-waves), twitch contractile properties, and motor unit discharges were recorded from the soleus muscle. In the low-force fatigue task, motor unit firing rate increased gradually over time, whereas the resting H-reflex was significantly depressed at 15% of endurance time and remained quasiconstant for the rest of the task. This suggests that the processes mediating the resting H-reflex depression are relatively independent of those modulating the motor unit firing rate during a low-force fatigue task. In the high-force fatigue task, a decline in the average motor unit discharge rate was accompanied by a decrease in the resting H-reflex amplitude and a prolongation of the twitch half-relaxation time (HRT) at the completion of the fatigue task. Overall, motor unit firing rate was modulated in parallel with changes in the twitch HRT, consistent with the muscle wisdom hypothesis.
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