ArticleGenome research2004
Large-scale integration of human genetic and physical maps.
Article in Genome research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- A novel approach of kinship determination based on the physical length of genetically shared regions of chromosomes.Genes & genomics · 2024Article
- A bioinformatics workflow for detecting signatures of selection in genomic data.Frontiers in genetics · 2014Article
- Second-generation genetic linkage map of catfish and its integration with the BAC-based physical map.G3 (Bethesda, Md.) · 2012Article
- A second generation integrated map of the rainbow trout (Oncorhynchus mykiss) genome: analysis of conserved synteny with model fish genomes.Marine biotechnology (New York, N.Y.) · 2012Article
- Further evidence for linkage of bipolar disorder to chromosomes 6 and 17 in a new independent pedigree series.Bipolar disorders · 2012Article
- A first generation integrated map of the rainbow trout genome.BMC genomics · 2011Article
- A genome-wide linkage study of bipolar disorder and co-morbid migraine: replication of migraine linkage on chromosome 4q24, and suggestion of an overlapping susceptibility region for both disorders on chromosome 20p11.Journal of affective disorders · 2010Article
- A first generation BAC-based physical map of the rainbow trout genome.BMC genomics · 2009Article
- A genome-wide Asian genetic map and ethnic comparison: the GENDISCAN study.BMC genomics · 2008Article
- Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb.Human genetics · 2008Article
- A comparative location database (CompLDB): map integration within and between species.Mammalian genome : official journal of the International Mammalian Genome Society · 2007Article
- A first generation BAC-based physical map of the channel catfish genome.BMC genomics · 2007Article
- The synaptonemal complex and meiotic recombination in humans: new approaches to old questions.Chromosoma · 2006Review
- Cotton genome mapping with new microsatellites from Acala 'Maxxa' BAC-ends.Molecular genetics and genomics : MGG · 2006Article
- A male-specific quantitative trait locus on 1p21 controlling human stature.Journal of medical genetics · 2005Article
- Article
- A genomewide scan of male sexual orientation.Human genetics · 2005Article
- SimPed: a simulation program to generate haplotype and genotype data for pedigree structures.Human heredity · 2005Article
- A combined linkage-physical map of the human genome.American journal of human genetics · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Genetic maps are used routinely in family-based linkage studies to identify the rough location of genes that influence human traits and diseases. Unlike physical maps, genetic maps are based on the amount of recombination occurring between adjacent loci rather than the actual number of bases separating them. Genetic maps are constructed by statistically characterizing the number of crossovers observed in parental meioses leading to the transmission of alleles to their offspring. Considerations such as the number of meioses observed, the heterozygosity and physical distance between the loci studied, and the statistical methods used can impact the construction and reliability of a genetic map. As is well known, poorly constructed genetic maps can have adverse effects on linkage mapping studies. With the availability of sequence-based maps, as well as genetic maps generated by different researchers (such as those generated by the Marshfield and deCODE groups), one can investigate the compatibility and properties of different maps. We have integrated information from the most current human genome sequence data (UCSC genome assembly Human July 2003) as well as 8399 microsatellite markers used in the Marshfield and deCODE maps to reconcile the these maps. Our efforts resulted in updated sex-specific genetic maps.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.