Evidence map›Paper›PMID 15139502›Full record

Trial reportDigestive diseases and sciences2004

Green banana and pectin improve small intestinal permeability and reduce fluid loss in Bangladeshi children with persistent diarrhea.

G H Rabbani, Telahun Teka, Shyamal Kumar Saha, Badiuz Zaman, Naseha Majid, Makhduma Khatun, Mohammad A Wahed, George J Fuchs

2 registry-linked trialsAbstract readClinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00732732 naterminatednot on this mapstarted 2008, after this paper: background citation

A Controlled Trail of Plantain Powder (Green Banana) in Infantile Diarrhea.

TypeinterventionalSponsorAugusta UniversityRan2008 to 2010Enrolled200ConditionsDiarrhea, InfantileArmsGreen banana powder, Microcrystalline cellulose
NCT04224168 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Pectin Use in Pediatric Intestinal Rehabilitation: Comparison Study of Liquid Pectin Versus Green Beans in Optimizing Enteral Nutrition in Short Bowel Syndrome Patients

TypeinterventionalSponsorLe Bonheur Children's HospitalRan2020 to 2021Enrolled15ConditionsShort Bowel SyndromeArmsGreen Beans, Liquid Pectin
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Review
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  15. Review
  16. Article
  17. Anti-diarrheal activity and toxicity of Learng Pid Samud recipe.African journal of traditional, complementary, and alternative medicines : AJTCAM · 2012
    Article
  18. Infectious diseases and vaccine sciences: strategic directions.Journal of health, population, and nutrition · 2008
    Review
  19. Review
  20. Chronic Diarrhea.Current treatment options in gastroenterology · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

G H RabbaniPhysiology Laboratory, Clinical Sciences Division, Clinical Service and Research Centre, ICDDR, B: Centre Health and Population Research, Bangladesh, GPO Box 128, Dhaka 1000, Bangladesh. rabbani@icddrb.org
Telahun Teka
Shyamal Kumar Saha
Badiuz Zaman
Naseha Majid
Makhduma Khatun
Mohammad A Wahed
George J Fuchs
International Centre for Diarrhoeal Disease Research · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effects of green banana and pectin (nondigestible, dietary sources of colonic shortchain fatty acids [SCFA]) on intestinal permeability, 57 boys (5-12 months) with persistent diarrhea (> or = 14 days) were given a week's treatment with a rice-based diet containing either cooked green banana (n = 19), pectin (n = 17), or rice diet alone (n = 21). Intestinal permeability was assessed before and after treatment by giving a lactulose-mannitol (LM) drink and measuring urinary recovery after 5 hr. Treatment with banana significantly (P < 0.05) reduced lactulose recovery, increased mannitol recovery, and decreased the LM ratio, indicating improvement of permeability. Pectin produced similar results. Permeability changes were associated with a 50% reduction in stool weights which correlated strongly (green banana, r2 = 0.84, pectin, r2 = 0.86) with the LM ratio. Green banana-derived and SCFA-mediated stimulation of colonic as well as small bowel absorption is responsible for their antidiarrheal effects. The antidiarrheal effects of green banana and pectin are mediated by improvement of small intestinal permeability in addition to their known colonotrophic effects.

Indexed as

Intestinal AbsorptionMusaAntidiarrhealsBangladeshDiarrhea, InfantileHumansInfantIntestinal MucosaLactuloseMaleMannitolOryzaPectinsPermeabilityAntidiarrhealsLactuloseMannitolPectins

Identifiers

PMID15139502
OpenAlexW2007444378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.