Evidence map›Paper›PMID 15138289›Full record

ArticleThe Journal of cell biology2004

Golgi duplication in Trypanosoma brucei.

Cynthia Y He, Helen H Ho, Joerg Malsam, Cecile Chalouni, Christopher M West, Elisabetta Ullu, Derek Toomre, Graham Warren

Abstract read
In one paragraph

Article in The Journal of cell biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Article
  2. The trypanosomatid dynamin-like protein associates with glycosomes.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multifunctional Roles of Sec13 Paralogues in the EuglenozoanbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Cellular landmarks of Trypanosoma brucei and Leishmania mexicana.Molecular and biochemical parasitology · 2019
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cynthia Y HeDepartment of Cell Biology, Ludwig Institute for Cancer Research, Yale University School of Medicine, 333 Cedar St., P.O. Box 208002, New Haven, CT 06520-8002, USA.
Helen H Ho
Joerg Malsam
Cecile Chalouni
Christopher M West
Elisabetta Ullu
Derek Toomre
Graham Warren

Funding

Wellcome Trust
6 · The paper itself

Abstract

Duplication of the single Golgi apparatus in the protozoan parasite Trypanosoma brucei has been followed by tagging a putative Golgi enzyme and a matrix protein with variants of GFP. Video microscopy shows that the new Golgi appears de novo, near to the old Golgi, about two hours into the cell cycle and grows over a two-hour period until it is the same size as the old Golgi. Duplication of the endoplasmic reticulum (ER) export site follows exactly the same time course. Photobleaching experiments show that the new Golgi is not the exclusive product of the new ER export site. Rather, it is supplied, at least in part, by material directly from the old Golgi. Pharmacological experiments show that the site of the new Golgi and ER export is determined by the location of the new basal body.

Indexed as

AnimalsCell CycleCells, CulturedEndoplasmic ReticulumFlagellaFluorescent Antibody TechniqueGolgi ApparatusGreen Fluorescent ProteinsLuminescent ProteinsMembrane ProteinsMicroscopy, ElectronMicroscopy, VideoProtein TransportProtozoan ProteinsTrypanosoma brucei bruceiGreen Fluorescent ProteinsLuminescent ProteinsMembrane ProteinsProtozoan Proteins

Identifiers

PMID15138289
PMCPMC2172185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.