Evidence map›Paper›PMID 15138190›Full record

ArticleClinical and diagnostic laboratory immunology2004

Interlaboratory reliability of microimmunofluorescence test for measurement of Chlamydia pneumoniae-specific immunoglobulin A and G antibody titers.

Alyson J Littman, Lisa A Jackson, Emily White, Mark D Thornquist, Charlotte A Gaydos, Thomas L Vaughan

Abstract read
In one paragraph

Article in Clinical and diagnostic laboratory immunology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2007
    Guideline
  2. Article
  3. Review
  4. Article
  5. Chlamydophila pneumoniae Infection and Its Role in Neurological Disorders.Interdisciplinary perspectives on infectious diseases · 2010
    Article
  6. Diagnostic test for etiologic agents of community-acquired pneumonia.Infectious disease clinics of North America · 2004
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alyson J LittmanFred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, M4 B402, Seattle, WA 98109-1024, USA. alittman@fhcrc.org
Lisa A Jackson
Emily White
Mark D Thornquist
Charlotte A Gaydos
Thomas L Vaughan

Funding

THE CAROTENE AND RETINOL EFFICACY TRIAL (CARET)U01CA063673 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GOODMAN, GARY E · 1994 to 2006
$13.0M
NCI NIH HHS U01 CA063673NCI NIH HHS U01 CA63673-07S2
6 · The paper itself

Abstract

To evaluate the reliability of Chlamydia pneumoniae-specific immunoglobulin G (IgG) and IgA antibody titers as measured by the microimmunofluorescence (MIF) test, we compared results from 392 individuals using a standard MIF protocol at two academic laboratories. The kappas for dichotomous titers (>/=16 versus <16) were 0.39 for IgA and 0.53 for IgG. Measurement error likely attenuates C. pneumoniae-disease associations; the magnitude of attenuation can be estimated from results of studies such as this one.

Indexed as

AgedAntibodies, BacterialChlamydophila InfectionsChlamydophila pneumoniaeFemaleFluorescent Antibody Technique, IndirectHumansImmunoglobulin AImmunoglobulin GMaleMiddle AgedReproducibility of ResultsAntibodies, BacterialImmunoglobulin AImmunoglobulin G

Identifiers

PMID15138190
PMCPMC404569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.