Evidence map›Paper›PMID 15133672›Full record

ReviewLangenbeck's archives of surgery2004

Ulcerative colitis: conservative management and long-term effects.

Tanja Kühbacher, Stefan Schreiber, Ulrich R Fölsch

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Gegen Qinlian decoction ameliorates experimental colitis in miceferroptosis pathway.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Proteomic analysis of colonic mucosal tissue from tuberculous and ulcerative colitis patients.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2012
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tanja KühbacherI. Medizinische Klinik, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Schittenhelmstrasse 12, 24105 Kiel, Germany. t.kuehbacher@mucosa.de
Stefan Schreiber
Ulrich R Fölsch
University of Lübeck · DEUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis is characterized by chronic inflammation of the colon. Typical symptoms are diarrhoea, rectal bleeding, abdominal pain and fever. The aetiology of the disease is unclear. The inflammation can be localized in the rectum or can extend to the left side or the whole colon. Treatment for induction and remission maintenance depends on the severity and extension of mucosal inflammation. Topical 5-aminosalicylates have been shown in studies to be the treatment of choice in mild to moderate ulcerative colitis. Oral 5-aminosalicylates can be used in distal, mild and moderate ulcerative colitis and for remission maintenance. For patients with a more extended or severe inflammation, oral or i.v. corticosteroids should be used. Patients with severe and/or chronic disease require immunosuppressive therapy with azathioprine or 6-mercaptopurine. For patients with severe, chronic, refractory disease, cyclosporine i.v. can be used. If no response to treatment is seen, proctocolectomy should be considered. Biological agents such as beta-Interferon seem to be effective in mild to moderately ulcerative colitis, but further studies have to be performed.

Indexed as

Administration, OralAdrenal Cortex HormonesAntibodies, MonoclonalAnti-Inflammatory Agents, Non-SteroidalAzathioprineColectomyColitis, UlcerativeCyclosporinsDouble-Blind MethodFollow-Up StudiesGastrointestinal AgentsHumansImmunosuppressive AgentsInfliximabInterferon-betaMercaptopurineAdrenal Cortex HormonesAntibodies, MonoclonalAnti-Inflammatory Agents, Non-SteroidalAzathioprineCyclosporinsGastrointestinal AgentsImmunosuppressive AgentsInfliximabInterferon-betaMercaptopurineMesalaminePlacebos

Identifiers

PMID15133672
OpenAlexW2070073693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.