ReviewCanadian journal of surgery. Journal canadien de chirurgie2004
Enteral nutrition and mucosal immunity: implications for feeding strategies in surgery and trauma.
Review in Canadian journal of surgery. Journal canadien de chirurgie, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00290524 (Prospective, Multicentric, Randomized Phase III Study Comparing Early Oral Alimentation to Nil Per Os Diet After Colorectal Surgery), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective, Multicentric, Randomized Phase III Study Comparing Early Oral Alimentation to Nil Per Os Diet After Colorectal Surgery
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Fiber and prebiotic supplementation in enteral nutrition: A systematic review and meta-analysis.World journal of gastroenterology · 2015Pooled it
- Enteral versus parenteral nutrition in auto-HCT: a randomized controlled trial on clinical outcomes and gut microbiome dynamics.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Exploring choices of early nutritional support for patients with sepsis based on changes in intestinal microecology.World journal of gastroenterology · 2023Trial
- Moderately high-protein enteral formula improved retinol-binding protein in tube-fed patients: A multicentre open study.Nutrition and health · 2017Trial
- Evaluation of guideline adherence in enteral nutrition practices among ICU patients: a point prevalence study.BMJ open · 2026Observational
- Gastrointestinal axis in post-traumatic sepsis: from molecular mechanisms to translational perspectives.Frontiers in immunology · 2026Review
- Immunomodulatory Effects of Juzentaihoto on Fas-Mediated Apoptosis: Insights from Cancer Patients and In Vitro Models.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Multimodal Prehabilitation in Major Abdominal Surgery-Rationale, Modalities, Results and Limitations.Medicina (Kaunas, Lithuania) · 2025Review
- Clinical analysis of risk factors for diarrhea associated with enteral nutrition in post-craniocerebral surgery patients.Frontiers in nutrition · 2025Article
- Nutritional Optimization of the Surgical Patient: A Narrative Review.Advances in nutrition (Bethesda, Md.) · 2025Review
- Effect of taurine supplementation on preventing ventilator-associated pneumonia in pediatrics under mechanical ventilation, a randomized controlled double-blind clinical trial.Frontiers in pediatrics · 2024Article
- Diamond-shaped versus side-to-side anastomotic duodenoduodenostomy in laparoscopic management of annular pancreas in children: a single-center retrospective comparative study.Translational pediatrics · 2023Article
- Re-examining chemically defined liquid diets through the lens of the microbiome.Nature reviews. Gastroenterology & hepatology · 2021Review
- Therapeutic Efficacy of Nasoenteric Tube Feeding in Children Needing Enteral Nutrition.Frontiers in pediatrics · 2021Article
- Crosstalk Between Intestinal Microbiota Derived Metabolites and Tissues in Allogeneic Hematopoietic Cell Transplantation.Frontiers in immunology · 2021Review
- Utilization of Intensive Care Unit Nutrition Consultation Is Associated With Reduced Mortality.JPEN. Journal of parenteral and enteral nutrition · 2020Article
- Short chain fatty acids: Postbiotics/metabolites and graft versus host disease colitis.Seminars in hematology · 2020Review
- Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults.Einstein (Sao Paulo, Brazil) · 2020Article
- The Gut Microbiota and Hematopoietic Stem Cell Transplantation: Challenges and Potentials.Journal of innate immunity · 2019Review
- Use of Enteral Nutrition for Gastrointestinal Bleeding Prophylaxis in the Critically Ill: Review of Current Literature.Current nutrition reports · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic inflammatory responses to severe trauma and surgical illnesses may be partly responsible for numerous complications, including sepsis, multiple organ failure and unregulated hypermetabolism leading to protein-calorie malnutrition. The integrity of the gastrointestinal tract appears to be an important factor in the pathogenesis of the systemic inflammatory response and sepsis. Resuscitation and nutrition support strategies for preserving gut mucosal integrity have therefore been strongly promoted. This review summarizes the scientific rationale for emphasizing enteral nutritional support of surgical patients, discusses some important limitations of enteral feeding and argues for a flexible approach to nutrition support for these complex patients.
Indexed as
Identifiers
15132464PMC3211926W46497072What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.