ArticleJournal of clinical microbiology2004
Detection of specific antibodies to severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein for serodiagnosis of SARS coronavirus pneumonia.
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04395924 (Maternal-Foetal Transmission of COVID-19), which is not on this map. Cited by 78 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Maternal-Foetal Transmission of COVID-19
Who cites it
78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Cesarean Section or Vaginal Delivery to Prevent Possible Vertical Transmission From a Pregnant Mother Confirmed With COVID-19 to a Neonate: A Systematic Review.Frontiers in medicine · 2021Pooled it
- Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2020Pooled it
- Seroprevalence of IgG antibodies to SARS-coronavirus in asymptomatic or subclinical population groups.Epidemiology and infection · 2006Pooled it
- Article
- Next-Generation Vaccines Against COVID-19 Variants: Beyond the Spike Protein.Zoonoses (Shannon, Ireland) · 2023Article
- SARS-CoV-2 Seroprevalence among Health-Care Workers in Isfahan, Iran.Advanced biomedical research · 2023Article
- Research progress in laboratory detection of SARS-CoV-2.Irish journal of medical science · 2022Review
- Maternal-Fetal Implications of SARS CoV-2 Infection during Pregnancy, Viral, Serological Analyses of Placenta and Cord Blood.International journal of environmental research and public health · 2022Article
- Recent advances in immunoassay technologies for the detection of human coronavirus infections.Frontiers in cellular and infection microbiology · 2022Review
- Antigen Specific Humoral and Cellular Immunity Following SARS-CoV-2 Vaccination in ANCA-Associated Vasculitis Patients Receiving B-Cell Depleting Therapy.Frontiers in immunology · 2022Article
- Long-term monitoring of the development and extinction of IgA and IgG responses to SARS-CoV-2 infection.Journal of medical virology · 2021Article
- Exploring Pregnancy Outcomes Associated with SARS-CoV-2 Infection.Medicina (Kaunas, Lithuania) · 2021Article
- SARS-COV-2 seroprevalence among employees of a University Hospital in Belgium during the 2020 COVID-19 outbreak (COVEMUZ-study).Epidemiology and infection · 2021Article
- Effects of Infection with SARS-CoV-2 on the Male and Female Reproductive Systems: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2021Review
- Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies.Translational research : the journal of laboratory and clinical medicine · 2021Article
- A Sensitive and Specific Competitive Enzyme-Linked Immunosorbent Assay for Serodiagnosis of COVID-19 in Animals.Microorganisms · 2021Article
- A novel highly quantitative and reproducible assay for the detection of anti-SARS-CoV-2 IgG and IgM antibodies.Scientific reports · 2021Article
- The role of serum specific- SARS-CoV-2 antibody in COVID-19 patients.International immunopharmacology · 2021Review
- The variability of the serological response to SARS-corona virus-2: Potential resolution of ambiguity through determination of avidity (functional affinity).Journal of medical virology · 2021Review
- Clinical evaluation of SARS-CoV-2 point-of-care antibody tests.Pathology · 2020Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the evaluation of recombinant severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) nucleocapsid protein enzyme-linked immunosorbent assay (ELISA)-based antibody tests for serodiagnosis of SARS-CoV pneumonia and compare the sensitivities and specificities of this ELISA for detection of immunoglobulin G (IgG), IgM, IgA, and their combinations with serum samples from 149 healthy blood donors who donated blood 3 years ago as controls and 106 SARS-CoV pneumonia patients in Hong Kong. The specificities of the ELISA for IgG, IgM, and IgA detection were 95.3, 96.6, and 96.6%, respectively, with corresponding sensitivities of 94.3, 59.4, and 60.4%, respectively. The present ELISA appears to be a sensitive test for serodiagnosis of SARS-CoV pneumonia, is much more economical and less labor-intensive than the indirect immunofluorescence assay, and does not require cultivation of SARS-CoV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.