ArticleJournal of clinical microbiology2004
Detection of Candida in concentrated oral rinse cultures by real-time PCR.
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
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- Oral Candidal Colonization in Patients with Different Prosthetic Appliances.Journal of fungi (Basel, Switzerland) · 2021Article
- Clinical Characteristics and Relevance of OralJournal of fungi (Basel, Switzerland) · 2021Article
- Relationship Between the Quantity of Oral Candida and Systemic Condition/Diseases of the Host: Oral Candida Increases with Advancing Age and Anemia.Mycopathologia · 2019Article
- Characterization of Oral Microbiota in Removable Dental Prosthesis Users: Influence of Arterial Hypertension.BioMed research international · 2017Article
- Advanced removal ofChemical engineering journal (Lausanne, Switzerland : 1996) · 2016Article
- Candida albicans Carriage in Children with Severe Early Childhood Caries (S-ECC) and Maternal Relatedness.PloS one · 2016Article
- Candida concentrations determined following concentrated oral rinse culture reflect clinical oral signs.BMC oral health · 2015Article
- Metabolomics reveals differential levels of oral metabolites in HIV-infected patients: toward novel diagnostic targets.Omics : a journal of integrative biology · 2013Article
- The Changing Epidemiology of Oropharyngeal Candidiasis in Patients with HIV/AIDS in the Era of Antiretroviral Therapy.AIDS research and treatment · 2012Article
- Antifungal drug resistance of oral fungi.Odontology · 2010Review
- Characterization of the oral fungal microbiome (mycobiome) in healthy individuals.PLoS pathogens · 2010Article
- High-throughput identification and quantification of Candida species using high resolution derivative melt analysis of panfungal amplicons.The Journal of molecular diagnostics : JMD · 2010Article
- Real-Time PCR: Revolutionizing Detection and Expression Analysis of Genes.Current genomics · 2007Article
- Development of novel real-time PCR assays for detection and differentiation of eleven medically important Aspergillus and Candida species in clinical specimens.Journal of clinical microbiology · 2007Article
- Development and clinical application of a panfungal PCR assay to detect and identify fungal DNA in tissue specimens.Journal of clinical microbiology · 2007Article
- Real-time PCR in clinical microbiology: applications for routine laboratory testing.Clinical microbiology reviews · 2006Review
- Development of a DNA microarray for detection and identification of fungal pathogens involved in invasive mycoses.Journal of clinical microbiology · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of oral candidosis has increased in recent years, largely as a result of the emergence of human immunodeficiency virus infection and the more widespread use of immunosuppressive chemotherapy. This development has been associated with a need for more reliable methods for the detection of Candida. The present study assessed the performance of a real-time PCR and two block-based PCRs for the detection of Candida in 193 concentrated oral rinse culture (CRC) specimens. A total of 102 CRC specimens were positive by culture for Candida; and 96, 90, and 75 of these were also positive by real-time, N18-specific, and internal transcribed spacer (ITS)-specific PCRs, respectively. The five false-negative results by the real-time PCR were all non-Candida albicans positive by culture. Of the 91 culture-negative CRC specimens, 20, 41, and 44 were positive by the real-time PCR and the N18- and ITS-specific PCRs, respectively. All three PCRs detected fungal DNA in 8 culture-negative CRC specimens, with a further 30 being positive by two of the three PCRs. A total of 32 CRC specimens were Candida free by all methods. In summary, a real-time PCR that provides a sensitive, specific, and rapid alternative technique for detection of Candida in the mouth is described.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.