ArticleHealth and quality of life outcomes2004
Women with coronary artery disease report worse health-related quality of life outcomes compared to men.
Article in Health and quality of life outcomes, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
45 citing papers in PubMed.
- Influence of explanatory and confounding variables on HRQoL after controlling for measurement bias and response shift in measurement.Expert review of pharmacoeconomics & outcomes research · 2013Trial
- Systolic blood pressure and subjective well-being in patients with coronary artery disease.Clinical cardiology · 2009Trial
- Gender differences in recovery outcomes after an early recovery symptom management intervention.Heart & lung : the journal of critical careTrial
- A comprehensive analysis of female participation in cardiovascular trials involving the WCN investigator network.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
- Exploring Factors Affecting Health-Related Quality of Life in Coronary Artery Disease Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Measuring health-related quality of life in cardiovascular disease using a novel patient-centred and disease-specific patient-reported outcome measure.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- The relationship between resting metabolic rate and quality of life is moderated by age and body composition in women: a cross-sectional study.BMC women's health · 2024Article
- Comparison of patients undergoing protected high risk percutaneous coronary intervention using either intravascular lithotripsy or rotational atherectomy.Frontiers in cardiovascular medicine · 2024Article
- Assessment of health-related quality of life in patients with heart failure: a cross-sectional study in Saudi Arabia.Health and quality of life outcomes · 2022Article
- Measurement invariance of the Seattle Angina Questionnaire in coronary artery disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- The Use of Patient Reported Outcome Measures (PROMs) 6 Months Post-Stroke and Their Association with the National Institute of Health Stroke Scale (NIHSS) on Admission to Hospital.Geriatrics (Basel, Switzerland) · 2021Article
- Exercise tolerance and quality of life in patients with known or suspected coronary artery disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Article
- Gender differences in quality of life in coronary artery disease patients with comorbidities undergoing coronary revascularization.PloS one · 2020Article
- Sex and gender disparities in the epidemiology and outcomes of chronic kidney disease.Nature reviews. Nephrology · 2018Review
- Lifetime traumatic events, health-related quality of life, and satisfaction with life in older adults.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Article
- Impaired Health Status, Psychological Distress, and Personality in Women and Men With Nonobstructive Coronary Artery Disease: Sex and Gender Differences: The TWIST (Tweesteden Mild Stenosis) Study.Circulation. Cardiovascular quality and outcomes · 2017Observational
- Socioeconomic inequalities in health-related quality of life between men and women, 5 years after a coronary angiography.Health and quality of life outcomes · 2016Article
- Association of individual and community factors with C-reactive protein and 25-hydroxyvitamin D: Evidence from the National Health and Nutrition Examination Survey (NHANES).SSM - population health · 2016Article
- The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan.Environmental health and preventive medicine · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough there have been substantial medical advances that improve the outcomes following cardiac ischemic events, gender differences in the treatment and course of recovery for patients with coronary artery disease (CAD) continue to exist. There is a general paucity of data comparing the health related quality of life (HRQOL) in men and women undergoing treatment for CAD. The purpose of this study was to compare HRQOL outcomes of men and women in Alberta, at one-year following initial catheterization, after adjustment for known demographic, co-morbid, and disease severity predictors of outcome.
methodThe HRQOL outcome data were collected by means of a self-reported questionnaire mailed to patients on or near the one-year anniversary of their initial cardiac catheterization. Using the Seattle Angina Questionnaire (SAQ), 5 dimensions of HRQOL were measured: exertional capacity, anginal stability, anginal frequency, quality of life and treatment satisfaction. Data from the APPROACH registry were used to risk-adjust the SAQ scale scores. Two analytical strategies were used including general least squares linear modeling, and proportional odds modeling sometimes referred to as the "ordinal logistic modeling".
results3392 (78.1%) patients responded to the follow-up survey. The adjusted proportional odds ratios for men relative to women (PORs > 1 = better) indicated that men reported significantly better HRQOL on all 5 SAQ dimensions as compared to women. (PORs: Exertional Capacity 3.38 (2.75-4.15), Anginal Stability 1.23 (1.03-1.47), Anginal Frequency 1.70 (1.43-2.01), Treatment Satisfaction 1.27 (1.07-1.50), and QOL 1.74 (1.48-2.04).
conclusionsWomen with CAD consistently reported worse HRQOL at one year follow-up compared to men. These findings underline the fact that conclusions based on research performed on men with CAD may not be valid for women and that more gender-related research is needed. Future studies are needed to further examine gender differences in psychosocial adjustment following treatment for CAD, as adjustment for traditional clinical variables fails to explain sex differences in health related quality of life outcomes.
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