ReviewMolecular neurobiology2004
Invertebrates yield a plethora of atypical guanylyl cyclases.
Review in Molecular neurobiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 63 citations in OpenAlex.
- IFT88 maintains sensory function by localising signalling proteins alongLife science alliance · 2024Article
- A FRET-based cGMP biosensor inmicroPublication biology · 2023Article
- ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans.PLoS biology · 2022Article
- Context-dependent reversal of odorant preference is driven by inversion of the response in a single sensory neuron type.PLoS biology · 2022Article
- Oxygen sensing in crustaceans: functions and mechanisms.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Review
- Compartmentalized cGMP Responses of Olfactory Sensory Neurons inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- The Signaling Pathway of Caenorhabditis elegans Mediates Chemotaxis Response to the Attractant 2-Heptanone in a Trojan Horse-like Pathogenesis.The Journal of biological chemistry · 2016Article
- De Novo Analysis of the Transcriptome of Meloidogyne enterolobii to Uncover Potential Target Genes for Biological Control.International journal of molecular sciences · 2016Article
- Article
- Receptor-Type Guanylyl Cyclase at 76C (Gyc76C) Regulates De Novo Lumen Formation during Drosophila Tracheal Development.PloS one · 2016Article
- Receptor Guanylyl Cyclases in Sensory Processing.Frontiers in endocrinology · 2016Review
- The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in Caenorhabditis elegans.Genetics · 2015Article
- Defining specificity determinants of cGMP mediated gustatory sensory transduction in Caenorhabditis elegans.Genetics · 2013Article
- Receptor guanylyl cyclase Gyc76C is required for invagination, collective migration and lumen shape in the Drosophila embryonic salivary gland.Biology open · 2013Article
- Receptor-type guanylyl cyclase Gyc76C is required for development of the Drosophila embryonic somatic muscle.Biology open · 2012Article
- Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster.PloS one · 2012Article
- Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways.Frontiers in bioscience (Landmark edition) · 2011Review
- Probing domain interactions in soluble guanylate cyclase.Biochemistry · 2011Article
- PKG-mediated MAPK signaling is necessary for long-term operant memory in Aplysia.Learning & memory (Cold Spring Harbor, N.Y.) · 2011Article
- Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Invertebrate model systems have a long history of generating new insights into neuronal signaling systems. This review focuses on cyclic GMP signaling and describes recent advances in understanding the properties and functions of guanylyl cyclases in invertebrates. The sequencing of three invertebrate genomes has provided a complete catalog of the guanylyl cyclases in C. elegans, Drosophila, and the mosquito Anopheles gambiae. Using this data and that from cloned guanylyl cyclases in Manduca sexta, C. elegans, and Drosophila, plus predictions and models from vertebrate guanylyl cyclases, evidence is presented that there is a much broader array of properties for these enzymes than previously realized. In addition to the classic homodimeric receptor guanylyl cyclases, C. elegans has at least two receptor guanylyl cyclases that are predicted to require heterodimer formation for activity. Soluble guanylyl cyclases are generally recognized as being obligate heterodimers that are activated by nitric oxide (NO). Some of the soluble guanylyl cyclases in C. elegans may heterodimeric, but all appear to be insensitive to NO. The beta2 soluble guanylyl cyclase subunit in mammals and similar ones in Manduca and Drosophila are active in the absence of additional subunits and there is evidence that Drosophila and Anopheles also express an additional subunit that enhances this activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.