ArticleProceedings of the National Academy of Sciences of the United States of America2004
Lipids in the inner membrane of dormant spores of Bacillus species are largely immobile.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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Who cites it
82 citing papers in PubMed, 203 citations in OpenAlex.
- Desiccation tolerance as a driver of environmental persistence and transmission in nosocomial bacterial pathogens.Infection and immunity · 2026Review
- YpeB stability affects germination possibly through delaying SleB activity inJournal of bacteriology · 2026Article
- Decoding Biothreats With FT-ICR-MS: Metabotyping of Bacillus cereus Spores Through Untargeted Metabolomics.Journal of mass spectrometry : JMS · 2026Article
- Preparation of Spores with the 70:30 Method.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Early activation of bioenergetic metabolism powers bacterial spore germination.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Resistance and germination of spores ofJournal of bacteriology · 2025Article
- Bacterially grown living materials with resistant and on-demand functionality.Science advances · 2025Article
- SpoIIIL is a forespore factor required for efficient cell-cell signalling during Bacillus subtilis sporulation.PLoS genetics · 2025Article
- Germination and Heat Resistance ofFoods (Basel, Switzerland) · 2025Article
- Effects of combining lysozyme, ultrasound, and heat treatments on the inactivation of Bacillus subtilis spores.Archives of microbiology · 2025Article
- Effects of Aqua-Glycerol Uptake Facilitator Protein GlpF on Spore Germination ofFoods (Basel, Switzerland) · 2025Article
- Bile acids as germinants for Clostridioides difficile spores, evidence of adaptation to the gut?FEMS microbiology reviews · 2025Review
- Combination of fluorescent reagents with 2-(4-aminophenyl) benzothiazole and safranin O was useful for analysis of spore structure, indicating the diversity ofFrontiers in microbiology · 2025Article
- The small acid-soluble proteins of spore-forming organisms: similarities and differences in function.Anaerobe · 2024Review
- Multifactorial resistance ofApplied and environmental microbiology · 2024Article
- Host-defense piscidin peptides as antibiotic adjuvants against Clostridioides difficile.PloS one · 2024Article
- Clostridioides difficile Sporulation.Advances in experimental medicine and biology · 2024Review
- A unique sigma/anti-sigma system in the actinomycete Actinoplanes missouriensis.Nature communications · 2023Article
- A Family of Spore Lipoproteins Stabilizes the Germination Apparatus by Altering Inner Spore Membrane Fluidity inJournal of bacteriology · 2023Article
- A coating of lipoproteins provides a stabilizing environment on the inner membrane ofJournal of bacteriology · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial spores of various Bacillus species are impermeable or exhibit low permeability to many compounds that readily penetrate germinated spores, including methylamine. We now show that a lipid probe in the inner membrane of dormant spores of Bacillus megaterium and Bacillus subtilis is largely immobile, as measured by fluorescence redistribution after photobleaching, but becomes free to diffuse laterally upon spore germination. The lipid immobility in and the slow permeation of methylamine through the inner membrane of dormant spores may be due to a significant (1.3- to 1.6-fold) apparent reduction of the membrane surface area in the dormant spore relative to that in the germinated spore, but is not due to the dormant spore's high levels of dipicolinic acid and divalent cations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.