Evidence map›Paper›PMID 15126494›Full record

ArticleJournal of bacteriology2004

-1 frameshifting at a CGA AAG hexanucleotide site is required for transposition of insertion sequence IS1222.

Nina Mejlhede, Patricia Licznar, Marie-Françoise Prère, Norma M Wills, Raymond F Gesteland, John F Atkins, Olivier Fayet

Abstract read
In one paragraph

Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Productive mRNA stem loop-mediated transcriptional slippage: Crucial features in common with intrinsic terminators.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  5. Article
  6. Article
  7. FSDB: a frameshift signal database.Computational biology and chemistry · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nina MejlhedeLaboratoire de Microbiologie et Génétique Moléculaire, UMR5100 Centre National de la Recherche Scientifique et Université Paul Sabatier, Toulouse 31062, France.
Patricia Licznar
Marie-Françoise Prère
Norma M Wills
Raymond F Gesteland
John F Atkins
Olivier Fayet
University of Utah · USLaboratoire de Microbiologie et Génétique Moléculaires · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

RECODING--DYNAMIC REPROGRAMMING OF GENETIC READOUTR01GM048152 · NIGMS · UNIVERSITY OF UTAH · PI ATKINS, JOHN F. · 1992 to 2004
$2.1M
NIGMS NIH HHS R01 GM048152NIGMS NIH HHS R01-GM48152
6 · The paper itself

Abstract

The discovery of programmed -1 frameshifting at the hexanucleotide shift site CGA_AAG, in addition to the classical X_XXY_YYZ heptanucleotide shift sequences, prompted a search for instances among eubacterial insertion sequence elements. IS1222 has a CGA_AAG shift site. A genetic analysis revealed that frameshifting at this site is required for transposition.

Indexed as

DNA Transposable ElementsFrameshifting, RibosomalBase SequenceMolecular Sequence DataRahnellaDNA Transposable Elements

Identifiers

PMID15126494
PMCPMC400620
OpenAlexW2119883801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.