ArticleGenetics2004
Molecular and functional analysis of scalloped recessive lethal alleles in Drosophila melanogaster.
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Validating upstream regulators of Yorkie activity in Hippo signaling throughDevelopment (Cambridge, England) · 2018Article
- Mef2 interacts with the Notch pathway during adult muscle development in Drosophila melanogaster.PloS one · 2014Article
- Expression and function of scalloped during Drosophila development.Developmental dynamics : an official publication of the American Association of Anatomists · 2013Article
- Identification of a classical bipartite nuclear localization signal in the Drosophila TEA/ATTS protein scalloped.PloS one · 2011Article
- Vestigial is required during late-stage muscle differentiation in Drosophila melanogaster embryos.Molecular biology of the cell · 2010Article
- Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.PLoS genetics · 2010Article
- Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc.Genes & development · 2009Article
- Genomic consequences of background effects on scalloped mutant expressivity in the wing of Drosophila melanogaster.Genetics · 2009Article
- Alternative requirements for Vestigial, Scalloped, and Dmef2 during muscle differentiation in Drosophila melanogaster.Molecular biology of the cell · 2009Article
- YAP regulates neural progenitor cell number via the TEA domain transcription factor.Genes & development · 2008Article
- Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.Molecular and cellular biology · 2008Article
- Article
- Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Drosophila melanogaster scalloped (sd) gene is a homolog of the human TEF-1 gene and is a member of the TEA/ATTS domain-containing family of transcription factors. In Drosophila, sd is involved in wing development as well as neural development. Herein, data are presented from a molecular analysis of five recessive lethal sd alleles. Only one of these alleles complements a viable allele associated with an sd mutant wing phenotype, suggesting that functions important for wing development are compromised by the noncomplementing alleles. Two of the wing noncomplementing alleles have mutations that help to define a VG-binding domain for the SD protein in vivo, and another noncomplementing allele has a lesion within the TEA DNA-binding domain. The VG-binding domain overlaps with a domain important for viability of the fly, since two of the sd lethal lesions are located there. The fifth lethal affects a yet undefined motif lying just outside the VG-binding domain in the C-terminal direction that affects both wing phenotype and viability. This is the first example linking mutations affecting specific amino acids in the SD protein with phenotypic consequences for the organism.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.