ArticleGenome research2004
Two methods of whole-genome amplification enable accurate genotyping across a 2320-SNP linkage panel.
Article in Genome research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
66 citing papers in PubMed.
- Comparative evaluation of antioxidant, cytoprotective, and anti-arthritic activities of pomegranate peel powder and coarse powdered date seeds: implications for functional nutrition.Journal, genetic engineering & biotechnology · 2026Article
- Genetic Testing for Malignant Hyperthermia Susceptibility-Threading the Needle in the Haystack.Genes · 2025Review
- ddRAD Sequencing and DNA Barcoding.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Embryo biopsies for genomic selection in tropical dairy cattle.Animal reproduction · 2023Review
- Determination of Pleiotropic Effect of Warfarin inFrontiers in cardiovascular medicine · 2022Article
- Relevance of ddRADseq method for species and population delimitation of closely related and widely distributed wolf spiders (Araneae, Lycosidae).Scientific reports · 2021Article
- Bio and phyto-chemical effect of Amphora coffeaeformis extract against hepatic injury induced by paracetamol in rats.Molecular biology reports · 2018Article
- Article
- Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells.Oncotarget · 2017Article
- Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications.BMC cancer · 2017Article
- Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions.Scientific reports · 2017Article
- Building a lineage from single cells: genetic techniques for cell lineage tracking.Nature reviews. Genetics · 2017Review
- Workflow optimization of whole genome amplification and targeted panel sequencing for CTC mutation detection.NPJ genomic medicine · 2017Article
- Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue.Genome medicine · 2016Article
- Next-Generation Sequencing Workflow for NSCLC Critical Samples Using a Targeted Sequencing Approach by Ion Torrent PGM™ Platform.International journal of molecular sciences · 2015Article
- Slp-76 is a critical determinant of NK-cell mediated recognition of missing-self targets.European journal of immunology · 2015Article
- Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls.BMC cancer · 2015Article
- Human Nail Clippings as a Source of DNA for Genetic Studies.Open journal of epidemiology · 2015Article
- Impact of whole-genome amplification on the reliability of pre-transfer cattle embryo breeding value estimates.BMC genomics · 2014Article
- DNA methylation temporal profiling following peripheral versus central nervous system axotomy.Scientific data · 2014Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comprehensive genome scans involving many thousands of SNP assays will require significant amounts of genomic DNA from each sample. We report two successful methods for amplifying whole-genomic DNA prior to SNP analysis, multiple displacement amplification, and OmniPlex technology. We determined the coverage of amplification by analyzing a SNP linkage marker set that contained 2320 SNP markers spread across the genome at an average distance of 2.5 cM. We observed a concordance of >99.8% in genotyping results from genomic DNA and amplified DNA, strongly indicating the ability of both methods used to amplify genomic DNA in a highly representative manner. Furthermore, we were able to achieve a SNP call rate of >98% in both genomic and amplified DNA. The combination of whole-genome amplification and comprehensive SNP linkage analysis offers new opportunities for genetic analysis in clinical trials, disease association studies, and archiving of DNA samples.
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