ArticleEnvironmental health perspectives2004
Probability estimates for the unique childhood leukemia cluster in Fallon, Nevada, and risks near other U.S. Military aviation facilities.
Article in Environmental health perspectives, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An examination, with a meta-analysis, of studies of childhood leukaemia in relation to population mixing.British journal of cancer · 2012Pooled it
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- Infectious triggers and novel therapeutic opportunities in childhood B cell leukaemia.Nature reviews. Immunology · 2021Review
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- Geographic Variation in Cancer Incidence among Children and Adolescents in Taiwan (1995-2009).PloS one · 2015Article
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- Tungsten Toxicity in Plants.Plants (Basel, Switzerland) · 2012Review
- Unusual space-time patterning of the Fallon, Nevada leukemia cluster: Evidence of an infectious etiology.Chemico-biological interactions · 2012Article
- Comparison of size and geography of airborne tungsten particles in Fallon, Nevada, and Sweet Home, Oregon, with implications for public health.Journal of environmental and public health · 2012Article
- Increased childhood liver cancer mortality and arsenic in drinking water in northern Chile.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2008Article
- Heavy metals in water of the San Pedro River in Chihuahua, Mexico and its potential health risk.International journal of environmental research and public health · 2008Article
- Spatial patterns of tungsten and cobalt in surface dust of Fallon, Nevada.Environmental geochemistry and health · 2007Article
- Using lichen chemistry to assess airborne tungsten and cobalt in Fallon, Nevada.Environmental monitoring and assessment · 2007Article
- Temporal variability of tungsten and cobalt in Fallon, Nevada.Environmental health perspectives · 2007Article
- Investigating childhood leukemia in Churchill County, Nevada.Environmental health perspectives · 2007Article
- Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada.Environmental health perspectives · 2007Article
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Abstract
A unique cluster of childhood leukemia has recently occurred around the city of Fallon in Churchill County, Nevada. From 1999 to 2001, 11 cases were diagnosed in this county of 23,982 people. Exposures related to a nearby naval air station such as jet fuel or an infectious agent carried by naval aviators have been hypothesized as potential causes. The possibility that the cluster could be attributed to chance was also considered. We used data from the Surveillance, Epidemiology, and End Results Program (SEER) to examine the likelihood that chance could explain this cluster. We also used SEER and California Cancer Registry data to evaluate rates of childhood leukemia in other U.S. counties with military aviation facilities. The age-standardized rate ratio (RR) in Churchill County was 12.0 [95% confidence interval (CI), 6.0-21.4; p = 4.3 times symbol 10(-9)]. A cluster of this magnitude would be expected to occur in the United States by chance about once every 22,000 years. The age-standardized RR for the five cases diagnosed after the cluster was first reported was 11.2 (95% CI, 3.6-26.3). In contrast, the incidence rate was not increased in all other U.S. counties with military aviation bases (RR = 1.04; 95% CI, 0.97-1.12) or in the subset of rural counties with military aviation bases (RR = 0.72; 95% CI, 0.48-1.08). These findings suggest that the Churchill County cluster was unlikely due to chance, but no general increase in childhood leukemia was found in other U.S. counties with military aviation bases.
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