ArticleMycopathologia2004
Fluconazole and itraconazole susceptibility of vaginal yeast isolates from Slovakia.
Article in Mycopathologia, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 91 citations in OpenAlex.
- Superiority of biomimetic micelle-entrapped nanoporous silica xerogel to deliver poorly water-soluble itraconazole.RSC advances · 2022Article
- Virulence Factors as Promoters of Chronic Vulvovaginal Candidosis: A Review.Mycopathologia · 2021Review
- A Mycological and Molecular Epidemiologic Study on Onychomycosis and DeterminationFrontiers in cellular and infection microbiology · 2021Article
- Ibrexafungerp, a Novel Oral Triterpenoid Antifungal in Development: Overview of Antifungal Activity AgainstFrontiers in cellular and infection microbiology · 2021Review
- In vitro anticandidal potency of Syzygium aromaticum (clove) extracts against vaginal candidiasis.BMC complementary medicine and therapies · 2020Article
- High prevalence of itraconazole resistance amongCurrent medical mycology · 2019Article
- Chemical composition and antifungal effect of hydroalcoholic extract ofCurrent medical mycology · 2017Article
- Extracellular enzymes and susceptibility to fluconazole in Candida strains isolated from patients with vaginitis and healthy individuals.Jundishapur journal of microbiology · 2015Article
- Species distribution and susceptibility profile to fluconazole, voriconazole and MXP-4509 of 551 clinical yeast isolates from a Romanian multi-centre study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Article
- Detection of FUR1 Gene in 5-Flucytosine Resistant Candida Isolates in Vaginal Candidiasis Patients.Journal of clinical and diagnostic research : JCDR · 2013Article
- In vitro susceptibility of Candida species to four antifungal agents assessed by the reference broth microdilution method.TheScientificWorldJournal · 2013Article
- Evaluation of antifungal activity of medicinal plant extracts against oral Candida albicans and proteinases.Mycopathologia · 2011Article
- In vivo activity of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida species.BMC complementary and alternative medicine · 2011Article
- Oxidative stress response and virulence factors in Candida glabrata clinical isolates.Folia microbiologica · 2011Article
- Antifungal Activity of Brazilian Propolis Microparticles against Yeasts Isolated from Vulvovaginal Candidiasis.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Clinical efficacy and health implications of inconsistency in different production batches of antimycotic drugs in a developing country.Journal of pharmacy & bioallied sciences · 2011Article
- Correlation between azole susceptibilities, genotypes, and ERG11 mutations in Candida albicans isolates associated with vulvovaginal candidiasis in China.Antimicrobial agents and chemotherapy · 2010Article
- Molecular analysis of Candida glabrata clinical isolates.Mycopathologia · 2010Article
- Two cases of vaginitis caused by itraconazole-resistant Saccharomyces cerevisiae and a review of recently published studies.Mycopathologia · 2008Review
- Species distribution and antifungal susceptibility profile of oral candida isolates from HIV-infected patients in the antiretroviral therapy era.Mycopathologia · 2006Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vulvovaginal candidiasis is a common mucosal infection caused by opportunistic yeasts of the Candida genus. In this study, we isolated and identified the yeast species in the vagina of patients treated in the gynecology clinic and tested in vitro activities of fluconazole and itraconazole against 227 clinical yeast isolates by the NCCLS microdilution method. C. albicans (87.6%) was the most frequently identified species followed by C. glabrata (6.2%) and C. krusei (2.2%). Almost thirteen percent of yeast strains were resistant to fluconazole and 18.5% were resistant to itraconazole. Cross-resistance analyses of C. albicans isolates revealed that fluconazole resistance and itraconazole resistance were also associated with decreased susceptibilities to other azole derivatives mainly to ketoconazole and miconazole. At the same time no cross-resistance to polyene antibiotics amphotericin B and nystatin was observed. These results support the notion that antifungal agents used to treat vaginitis may be contributing to the drug resistance problem by promoting cross-resistance to a range of clinically used antifungals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.