ArticlePlant cell reports2004
Characterization of a multifunctional methyltransferase from the orchid Vanilla planifolia.
Article in Plant cell reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 45 citations in OpenAlex.
- Comprehensive metabolome characterization of leaves, internodes, and aerial roots of Vanilla planifolia by untargeted LC-MS and GC × GC-MS.Phytochemical analysis : PCA · 2025Article
- Genetic Engineering Approaches for the Microbial Production of Vanillin.Biomolecules · 2024Review
- Exploring the Volatile Profile ofFoods (Basel, Switzerland) · 2024Article
- Proteomic approach to identify the differentially abundant proteins during flavour development in tuberous roots of3 Biotech · 2021Article
- Distinct Roles for Bacterial and Fungal Communities During the Curing of Vanilla.Frontiers in microbiology · 2020Article
- Molecular Cloning and Characterization of aInternational journal of molecular sciences · 2018Article
- Vanillin biosynthetic pathways in plants.Planta · 2017Review
- A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia).BMC genomics · 2014Article
- Functional characterization of two new members of the caffeoyl CoA O-methyltransferase-like gene family from Vanilla planifolia reveals a new class of plastid-localized O-methyltransferases.Plant molecular biology · 2011Article
- Microbial production of biovanillin.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2010Article
- Evolution of novel O-methyltransferases from the Vanilla planifolia caffeic acid O-methyltransferase.Plant molecular biology · 2006Article
- UPR-independent dithiothreitol stress-induced genes in Aspergillus niger.Molecular genetics and genomics : MGG · 2005Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The final enzymatic step in the synthesis of the flavor compound vanillin (4-hydroxy-3-methoxybenzaldehyde) is believed to be methylation of 3,4-dihydroxybenzaldehyde. We have isolated and functionally characterized a cDNA that encodes a multifunctional methyltransferase from Vanilla planifolia tissue cultures that can catalyze the conversion of 3,4-dihydroxybenzaldehyde to vanillin, although 3,4-dihydroxybenzaldehyde is not the preferred substrate. The higher catalytic efficiency of the purified recombinant enzyme with the substrates caffeoyl aldehyde and 5-OH-coniferaldehyde, and its tissue distribution, suggest this methyltransferase may primarily function in lignin biosynthesis. However, since the enzyme characterized here does have 3,4-dihydroxybenzaldehyde-O-methyltransferase activity, it may be useful in engineering strategies for the synthesis of natural vanillin from alternate sources.
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