ReviewBMC musculoskeletal disorders2004
Roles of hyaluronan in bone resorption.
Review in BMC musculoskeletal disorders, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 50 citations in OpenAlex.
- Effect of intra-socket application of hyaluronic acid gel on soft and hard tissue healing following impacted mandibular third molars extraction (a randomized controlled clinical trial).BMC oral health · 2025Trial
- In vivo impact on rabbit subchondral bone of viscosupplementation with a hyaluronic acid antioxidant conjugate.BMC musculoskeletal disorders · 2024Article
- Biomimetic Hyaluronan Binding Biomaterials to Capture the Complex Regulation of Hyaluronan in Tissue Development and Function.Biomimetics (Basel, Switzerland) · 2024Review
- Mechanobiology of Hyaluronan: Connecting Biomechanics and Bioactivity in Musculoskeletal Tissues.Annual review of biomedical engineering · 2024Review
- Temporal response of an injectable calcium phosphate material in a critical size defect.Journal of orthopaedic surgery and research · 2021Article
- Chitosan in viscosupplementation: in vivo effect on rabbit subchondral bone.BMC musculoskeletal disorders · 2017Article
- Comparison of various SYSADOA for the osteoarthritis treatment: an experimental study in rabbits.BMC musculoskeletal disorders · 2015Article
- Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells.BioMed research international · 2015Review
- Modifications in bone matrix of estrogen-deficient rats treated with intermittent PTH.BioMed research international · 2015Article
- Evaluation of cardiovascular toxicity of carbon nanotubes functionalized with sodium hyaluronate in oral regenerative medicine.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014Article
- Hapln1a is required for connexin43-dependent growth and patterning in the regenerating fin skeleton.PloS one · 2014Article
- Regenerative potential of glycosaminoglycans for skin and bone.Journal of molecular medicine (Berlin, Germany) · 2012Review
- Unsatisfactory gene transfer into bone-resorbing osteoclasts with liposomal transfection systems.Journal of negative results in biomedicine · 2005Article
- Secretory products of breast cancer cells upregulate hyaluronan production in a human osteoblast cell line.Clinical & experimental metastasis · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyaluronan, an unsulfated glycosaminoglycan, while being closely linked to osteoclast function several years ago, has received little attention lately. Given recent new knowledge of hyaluronan's possible cell binding abilities, it is important to re-examine the role of this polysaccharide in bone homeostasis. DISCUSSION: Previously published data demonstrating a linkage between induction of hyaluronan synthesis and osteoclast-mediated bone resorption are reviewed. Suggestions are made involving the cell binding ability of hyaluronan and its potential to mediate osteoclast binding to bone surfaces and its potential to serve as a diffusion barrier and participate in the sealing zone required for osteoclast-mediated bone resorption. SUMMARY: This brief article summarizes previous studies linking HA to bone resorption and suggests roles for hyaluronan in the process of bone resorption.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.