ArticleBiophysical journal2004
Shape memory of human red blood cells.
Article in Biophysical journal, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- Red Blood Cell Deformability in Microfluidic Constrictions Under Flow and Wall Contact.Micromachines · 2026Article
- Modulatory effects of 6-Gingerol on erythrocyte deformability and morphology following lower extremity skeletal muscle ischemia-reperfusion injury in rats.Scientific reports · 2026Article
- Effects of the Mechanical Behaviors of Red Blood Cells on the Blood Flow.Advances in experimental medicine and biology · 2026Article
- Measuring the effect of repetitive stretching on the deformability of human red blood cells using optical tweezers.Scientific reports · 2025Article
- Artificial cells for in vivo biomedical applications through red blood cell biomimicry.Nature communications · 2024Review
- Lattice Boltzmann simulation of deformable fluid-filled bodies: progress and perspectives.Soft matter · 2024Review
- Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders.Science advances · 2023Article
- Article
- Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders.bioRxiv : the preprint server for biology · 2023Article
- The stress-free state of human erythrocytes: Data-driven inference of a transferable RBC model.Biophysical journal · 2023Article
- Shape transformations of red blood cells in the capillary and their possible connections to oxygen transportation.Journal of biological physics · 2022Article
- Red blood cell shape transitions and dynamics in time-dependent capillary flows.Biophysical journal · 2022Article
- Multimodal imaging reveals membrane skeleton reorganisation during reticulocyte maturation and differences in dimple and rim regions of mature erythrocytes.Journal of structural biology: X · 2022Article
- Modeling Red Blood Cell Viscosity Contrast Using Inner Soft Particle Suspension.Micromachines · 2021Article
- Microfluidic Obstacle Arrays Induce Large Reversible Shape Change in Red Blood Cells.Micromachines · 2021Article
- Effects of N-Acetylcysteine and N-Acetylcysteine Amide on Erythrocyte Deformability and Oxidative Stress in a Rat Model of Lower Extremity Ischemia-Reperfusion Injury.Cardiology research and practice · 2020Article
- Early Career Scientists' Guide to the Red Blood Cell - Don't Panic!Frontiers in physiology · 2020Article
- Heterogeneity of Red Blood Cells: Causes and Consequences.Frontiers in physiology · 2020Review
- Deformation and dynamics of erythrocytes govern their traversal through microfluidic devices with a deterministic lateral displacement architecture.Biomicrofluidics · 2019Article
- Emergent behaviors in RBCs flows in micro-channels using digital particle image velocimetry.Microvascular research · 2018Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human red cell can be deformed by external forces but returns to the biconcave resting shape after removal of the forces. If after such shape excursions the rim is always formed by the same part of the membrane, the cell is said to have a memory of its biconcave shape. If the rim can form anywhere on the membrane, the cell would have no shape memory. The shape memory was probed by an experiment called go-and-stop. Locations on the membrane were marked by spontaneously adhering latex spheres. Shape excursions were induced by shear flow. In virtually all red cells, a shape memory was found. After stop of flow and during the return of the latex spheres to the original location, the red cell shape was biconcave. The return occurred by a tank-tread motion of the membrane. The memory could not be eliminated by deforming the red cells in shear flow up to 4 h at room temperature as well as at 37 degrees C. It is suggested that 1). the characteristic time of stress relaxation is >80 min and 2). red cells in vivo also have a shape memory.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.