ArticleBiophysical journal2004
Tension in tubulovesicular networks of Golgi and endoplasmic reticulum membranes.
Article in Biophysical journal, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 131 citations in OpenAlex.
- Engineering principles in plant metabolism: integrating control, mechanics, and transport under dynamic environments.Plant physiology · 2026Review
- Bimodal Mechanical Response of Membrane Necks: Implications for the Nuclear Envelope.ACS nano · 2026Article
- Article
- Dynamical modelling of lipid droplet formation suggests a key function of membrane phospholipids.The FEBS journal · 2025Article
- Giant organelle vesicles to uncover intracellular membrane mechanics and plasticity.Nature communications · 2024Article
- Article
- Topological damping in an ultrafast giant cell.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Endoplasmic reticulum network heterogeneity guides diffusive transport and kinetics.Biophysical journal · 2023Article
- Model for ring closure in ER tubular network dynamics.Biophysical journal · 2023Article
- The yellow brick road to nuclear membrane mechanotransduction.APL bioengineering · 2022Review
- Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes.Annual review of biophysics · 2022Review
- Origin of gradients in lipid density and surface tension between connected lipid droplet and bilayer.Biophysical journal · 2021Article
- Nonlinear material and ionic transport through membrane nanotubes.Biochimica et biophysica acta. Biomembranes · 2021Article
- Intertwined and Finely Balanced: Endoplasmic Reticulum Morphology, Dynamics, Function, and Diseases.Cells · 2021Review
- Network organisation and the dynamics of tubules in the endoplasmic reticulum.Scientific reports · 2021Article
- Microtubule-independent movement of the fission yeast nucleus.Journal of cell science · 2021Article
- Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets.eLife · 2021Article
- Article
- Membrane Curvature, Trans-Membrane Area Asymmetry, Budding, Fission and Organelle Geometry.International journal of molecular sciences · 2020Review
- Biological lipid nanotubes and their potential role in evolution.The European physical journal. Special topics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endoplasmic reticulum (ER) and Golgi have robust bidirectional traffic between them and yet form distinct membrane compartments. Membrane tubules are pulled from large aggregates of ER or Golgi by microtubule motors to form ER tubulovesicular networks or Golgi tubules both in vivo and in vitro. The physical properties of membranes are critical for membrane traffic and organelle morphology. For example, tension applied to membranes can create tethers, drive membrane flow, and set the diameter of the tubules. Here, we formed ER and Golgi membrane networks in vitro and used optical tweezers to measure directly, for the first time, the membrane tensions of these organelles to clarify the possible role of tension in membrane flow. We report that higher forces are needed to form tethers from ER (18.6 +/- 2.8 pN) than from Golgi (11.4 +/- 1.4 pN) membrane tubules in vitro. Since ER tubules are smaller in diameter than Golgi tubules, it follows that Golgi networks have a lower tension than ER. The lower tension of the ER could be an explanation of how Golgi tubules can be rapidly drawn into the ER by tension-driven flow after fusion, as is observed in vivo.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.