Evidence map›Paper›PMID 15109430›Full record

ArticleEmerging infectious diseases2004

Immunofluorescence assay for serologic diagnosis of SARS.

Paul K S Chan, King-Cheung Ng, Rickjason C W Chan, Rebecca K Y Lam, Viola C Y Chow, Mamie Hui, Alan Wu, Nelson Lee, Florence H Y Yap, Frankie W T Cheng and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 62 citations in OpenAlex.

  1. Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2004
    Trial
  2. Article
  3. COVID-19 versus SARS: A comparative review.Journal of infection and public health · 2021
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Paul K S ChanDepartment of Microbiology, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People's Republic of China. paulkschan@cuhk.edu.hk
King-Cheung Ng
Rickjason C W Chan
Rebecca K Y Lam
Viola C Y Chow
Mamie Hui
Alan Wu
Nelson Lee
Florence H Y Yap
Frankie W T Cheng
Joseph J Y Sung
John S Tam
Chinese University of Hong Kong · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated an indirect immunofluorescence assay based on virus-infected cells for detecting anti-severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.

Indexed as

AdolescentAdultAntibodies, ViralChildChild, PreschoolCommunicable Diseases, EmergingFemaleFluorescent Antibody Technique, IndirectHong KongHumansMaleMiddle AgedReverse Transcriptase Polymerase Chain ReactionSevere Acute Respiratory SyndromeAntibodies, Viral

Identifiers

PMID15109430
PMCPMC3322771
OpenAlexW2143245040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.