Evidence map›Paper›PMID 15109346›Full record

ReviewJournal of general internal medicine2004

Inpatient diabetology. The new frontier.

Nicolas N Abourizk, Chaula K Vora, Parveen K Verma

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of general internal medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00700154 naterminatednot on this mapstarted 2011, after this paper: background citation

The Effect of Insulin Infusion on Metabolic Control and Inflammation in Diabetic Patients During Cardio-vascular Intervention and/or Treatment for Acute Foot Ulcer Infection.

TypeinterventionalSponsorKarolinska InstitutetRan2011 to 2020Enrolled40ConditionsDiabetes Mellitus, Insulin Resistance, Hyperglycemia, SurgeryArmsInsulin infusion
NCT00700362 withdrawnnot on this mapstarted 2011, after this paper: background citation

The Effect of Insulin-Glucose Infusion on Metabolic Control (Primary) and Inflammation (Secondary) in Diabetic Patients Treated for Acute Foot Ulcer Infection or Surgical Wound Infection

TypeobservationalSponsorKarolinska InstitutetRan2011 to 2016Enrolled0ConditionsDiabetes Mellitus, Insulin Resistance, Hyperglycemia, InfectionArmsInsulin infusion (aspart), Standard care
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. TeDia - A Telemedicine-Based Treatment Model for Inpatient and Interprofessional Diabetes Care.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019
    Article
  2. Article
  3. Practice tips. Insulin protocols for hospital management of diabetes.Canadian family physician Medecin de famille canadien · 2007
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicolas N AbourizkSaint Francis Hospital and Medical Center, Hartford, Conn. 06105, USA. nabouriz@stfranciscare.org
Chaula K Vora
Parveen K Verma
UConn Health · USUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tight glycemic control is now an imperative of outpatient diabetes care. The inpatient arena remains under the influence of an ineffective paradigm characterized by tolerance for hyperglycemia and a reluctance to use insulin intensively. This article is a call to action against the lip service paid to inpatient diabetes care. The compelling in vitro and in vivo evidence for the benefit of intensive insulin-mediated glycemic control is summarized. The linchpin of current inpatient care is a commonly used insulin sliding scale. This autopilot approach as the sole mode of treatment for inpatient hyperglycemia has been strongly condemned. Nevertheless, it continues to survive. The evidence supports the compelling argument that the adverse effect of hyperglycemia on hospital length of stay, morbidity, and mortality is substantial. Clinicians, nurses, administrators, and insurers ought to look critically at the prevailing paradigm and spearhead the much-needed revolution in inpatient diabetology. The issue of glycemic targets, the need for noninvasive blood glucose monitoring, and the role of nursing staff in this revolution are raised. We call for the banning of the insulin sliding scale use as the sole diabetes order. Also, the use of basal insulin via continuous intravenous insulin infusion or subcutaneous insulin analogs should be embraced. Educating nurses, house staff, and other frontline professionals in the adverse consequences of the current paradigm is essential. Inpatient glycemic control matters; clinical and financial outcomes are at stake. It behooves the health care system and the diabetic public to address the contemporary state of inpatient diabetology as soon as possible.

Indexed as

HospitalizationBlood GlucoseCritical CareDiabetes Mellitus, Type 2Drug Administration ScheduleEvidence-Based MedicineHumansHyperglycemiaHypoglycemic AgentsInsulinBlood GlucoseHypoglycemic AgentsInsulin

Identifiers

PMID15109346
PMCPMC1492248
OpenAlexW2317543399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.