ArticleImmunogenetics2004
In-silico identification of chicken immune-related genes.
Article in Immunogenetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- The Knob Domain of the Fiber-1 Protein Affects the Replication of Fowl Adenovirus Serotype 4.Microorganisms · 2024Article
- Functional prediction of de novo uni-genes from chicken transcriptomic data following infectious bursal disease virus at 3-days post-infection.BMC genomics · 2021Article
- Avian Immunome DB: an example of a user-friendly interface for extracting genetic information.BMC bioinformatics · 2020Article
- Transcriptomic analysis of immune response to bacterial lipopolysaccharide in zebra finch (Taeniopygia guttata).BMC genomics · 2019Article
- Immunostimulatory Activities of CpG-Oligodeoxynucleotides in Teleosts: Toll-Like Receptors 9 and 21.Frontiers in immunology · 2019Review
- Effects of Oral Probiotic Feeding on Toll-Like Receptor Gene Expression of the Chicken's Cecal Tonsil.Reports of biochemistry & molecular biology · 2018Article
- Toll-Like Receptors, Associated Biological Roles, and Signaling Networks in Non-Mammals.Frontiers in immunology · 2018Review
- RNA-seq Profiles of Immune Related Genes in the Spleen of Necrotic Enteritis-afflicted Chicken Lines.Asian-Australasian journal of animal sciences · 2015Article
- Characterisation of Toll-like receptors 4, 5 and 7 and their genetic variation in the grey partridge.Genetica · 2015Article
- Protein evolution of Toll-like receptors 4, 5 and 7 within Galloanserae birds.Genetics, selection, evolution : GSE · 2014Article
- Expression analysis of turkey (Meleagris gallopavo) toll-like receptors and molecular characterization of avian specific TLR15.Molecular biology reports · 2012Article
- Effect of toll-like receptor activation on thymosin beta-4 production by chicken macrophages.Molecular and cellular biochemistry · 2010Article
- Article
- Non-coding RNAs revealed during identification of genes involved in chicken immune responses.Immunogenetics · 2009Article
- Evolution of the chicken Toll-like receptor gene family: a story of gene gain and gene loss.BMC genomics · 2008Article
- Characterization of the opossum immune genome provides insights into the evolution of the mammalian immune system.Genome research · 2007Article
- Species-specific evolution of the FcR family in endothermic vertebrates.Immunogenetics · 2007Article
- Construction of a microarray specific to the chicken immune system: profiling gene expression in B cells after lipopolysaccharide stimulation.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2007Article
- Development of a chicken 5 K microarray targeted towards immune function.BMC genomics · 2006Article
- Identification and functional characterization of chicken toll-like receptor 5 reveals a fundamental role in the biology of infection with Salmonella enterica serovar typhimurium.Infection and immunity · 2005Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to increase the resources available in chicken, a large-scale expressed sequence tag (EST) project was recently undertaken, resulting in the addition of more than 330,000 sequences to the databases. With the sequencing of further EST collections, there are now more than 460,000 chicken EST sequences publicly available (http://www.ncbi.nlm.nih.gov/). Previous analyses of the EST data estimate that the chicken genome may contain up to 35,000 genes. However, human data indicate that there may only be around 25,000, although there may be many more transcripts than actual genes. Here we describe how we used a bioinformatics approach with this large EST collection in order to identify immune-related genes, many of which were previously unreported in the chicken. The ESTs include cytokines, chemokines, antigens, cell surface proteins, receptors and MHC-associated genes. The identification of these kinds of genes will allow further study of avian immunology and will pave the way for large-scale immune-related microarray experiments, giving new insight into functional and evolutionary studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.