Evidence map›Paper›PMID 15106224›Full record

SynthesisThe Cochrane database of systematic reviews2004

Ginkgo biloba for tinnitus.

M Hilton, E Stuart

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 11 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Guideline
  2. A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Pooled it
  3. Ginkgo biloba for tinnitus.The Cochrane database of systematic reviews · 2013
    Pooled it
  4. Ginkgo biloba extract for age-related macular degeneration.The Cochrane database of systematic reviews · 2013
    Pooled it
  5. Sound therapy (masking) in the management of tinnitus in adults.The Cochrane database of systematic reviews · 2012
    Pooled it
  6. Antidepressants for patients with tinnitus.The Cochrane database of systematic reviews · 2012
    Pooled it
  7. Anticonvulsants for tinnitus.The Cochrane database of systematic reviews · 2011
    Pooled it
  8. Pooled it
  9. Cognitive behavioural therapy for tinnitus.The Cochrane database of systematic reviews · 2010
    Pooled it
  10. Tinnitus Retraining Therapy (TRT) for tinnitus.The Cochrane database of systematic reviews · 2010
    Pooled it
  11. Ginkgo biloba for acute ischaemic stroke.The Cochrane database of systematic reviews · 2005
    Pooled it
  12. Trial
  13. Article
  14. HNO-Nachrichten · 2022
    Review
  15. Article
  16. Chronic tinnitus: an interdisciplinary challenge.Deutsches Arzteblatt international · 2013
    Review
  17. Article
  18. Article
  19. Complementary and alternative medicine use by otolaryngology patients: a paradigm for practitioners in all surgical specialties.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2010
    Article
  20. Emerging pharmacotherapy of tinnitus.Expert opinion on emerging drugs · 2009
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M HiltonRoyal Devon & Exeter Hospital, Barrack Rd, Exeter, Devon, UK, EX2 5DW.
E Stuart
Royal Devon and Exeter Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTinnitus can be described as the perception of sound in the absence of external acoustic stimulation. At present no specific therapy for tinnitus is acknowledged to be satisfactory in all patients. There are a number of reports in the literature suggesting that Ginkgo biloba may be effective in the management of tinnitus. However, there also appears to be a strong placebo effect in tinnitus management.

objectivesTo assess the effect of Ginkgo biloba in patients who are troubled by tinnitus. SEARCH STRATEGY: The Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library Issue 4 2003), MEDLINE (1966 - 2003), EMBASE (1974 - 2003), and reference lists of identified publications. Date of the most recent search was December 2003. SELECTION CRITERIA: Adults (18 years and over) complaining of tinnitus. Adults with a primary complaint of cerebral insufficiency where tinnitus forms part of the syndrome. DATA COLLECTION AND ANALYSIS: Both reviewers independently extracted data and assessed trials for quality. MAIN

resultsTwelve trials were identified from the search as being relevant to the review. Ten trials were excluded on methodological grounds. No trials of tinnitus in cerebral insufficiency reached a satisfactory standard for inclusion in the review. There was no evidence that Ginkgo biloba was effective for the primary complaint of tinnitus. The incidence of side effects was small. REVIEWERS'

conclusionsThe limited evidence did not demonstrate that Ginkgo biloba was effective for tinnitus which is a primary complaint. There was no reliable evidence to address the question of Ginkgo biloba for tinnitus associated with cerebral insufficiency.

Indexed as

Ginkgo bilobaPhytotherapyAdultHumansTinnitus

Identifiers

PMID15106224
OpenAlexW4246422373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.