ArticleArchives of disease in childhood2004
Chest physiotherapy, gastro-oesophageal reflux, and arousal in infants with cystic fibrosis.
Article in Archives of disease in childhood, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- The International Network on Oesophageal Atresia (INoEA) consensus guidelines on the transition of patients with oesophageal atresia-tracheoesophageal fistula.Nature reviews. Gastroenterology & hepatology · 2023Guideline
- Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis.The Cochrane database of systematic reviews · 2023Pooled it
- Standard (head-down tilt) versus modified (without head-down tilt) postural drainage in infants and young children with cystic fibrosis.The Cochrane database of systematic reviews · 2015Pooled it
- Non-nutritive sucking for gastro-oesophageal reflux disease in preterm and low birth weight infants.The Cochrane database of systematic reviews · 2014Pooled it
- Cystic Fibrosis Foundation evidence-based guidelines for management of infants with cystic fibrosis.The Journal of pediatrics · 2009Guideline
- Asymptomatic Erosive Esophagitis.Digestive diseases and sciences · 2025Review
- Airway clearance therapy in acute paediatric respiratory illness: A state-of-the-art review.The South African journal of physiotherapy · 2019Article
- Standard (head-down tilt) versus modified (without head-down tilt) postural drainage in infants and young children with cystic fibrosis.The Cochrane database of systematic reviews · 2018Review
- Airway-Clearance Techniques in Children and Adolescents with Chronic Suppurative Lung Disease and Bronchiectasis.Frontiers in pediatrics · 2017Review
- Chest Physiotherapy in the Pediatric Intensive Care Unit.Journal of pediatric intensive care · 2015Review
- Article
- From hemp seed and porcupine quill to HRCT: advances in the diagnosis and epidemiology of bronchiectasis.Archives of disease in childhood · 2005Review
- Musculoskeletal and neuromuscular interventions: a physical approach to cystic fibrosis.Journal of the Royal Society of Medicine · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostural drainage chest physiotherapy in infants with cystic fibrosis (CF) exacerbates gastro-oesophageal reflux (GOR) and may contribute to a more rapid deterioration in lung function.
aimsTo compare standard postural drainage chest physiotherapy (SPT) and a modified physiotherapy regimen (MPT) without head-down tilt, with regard to GOR, arousal state, and cardiorespiratory function.
methodsTwenty infants with CF underwent 30 hour oesophageal pH monitoring, during which four chest physiotherapy sessions were administered (day 1: MPT-SPT; day 2: SPT-MPT). Arousal state, heart rate, and oxygen saturation were documented for each of the physiotherapy positions (supine, prone, right lateral, and left lateral with (SPT) or without (MPT) 30 degrees head-down tilt).
resultsSignificantly more reflux episodes occurred during SPT than during MPT, but there were no significant differences in median episode duration or fractional reflux time. During SPT, left lateral positioning was associated with fewer reflux episodes compared to other positions. During supine and prone positioning, more reflux episodes occurred during SPT than during MPT. Infants were significantly more likely to be awake or cry during SPT. There was a significant association between crying and reflux episodes for SPT. Non-nutritive sucking was associated with a significant reduction in reflux episodes during SPT. Oxygen saturation during SPT was significantly lower during crying and other waking, and non-nutritive sucking during SPT was associated with a significant increase in oxygen saturation.
conclusionsSPT is associated with GOR, distressed behaviour, and lower oxygen saturation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.