ArticleTrends in molecular medicine2004
Virus-induced neurobehavioral disorders: mechanisms and implications.
Article in Trends in molecular medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions - A Narrative Review.Health science reports · 2026Article
- Viruses and psychiatric disorders: We have not crossed the borderline from hypothesis to proof yet (Review).Molecular medicine reports · 2025Review
- Psychiatric disorders in adolescents living with HIV in Botswana.AIDS research and therapy · 2023Article
- Developing brain under renewed attack: viral infection during pregnancy.Frontiers in neuroscience · 2023Review
- Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive-compulsive disorder.BMC psychiatry · 2022Article
- Contribution of Pro-Inflammatory Molecules Induced by Respiratory Virus Infections to Neurological Disorders.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Neurological complications of pandemic A(H1N1)2009pdm, postpandemic A(H1N1)v, and seasonal influenza A.Brain and behavior · 2021Article
- Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Antennae hold a key to Varroa-sensitive hygiene behaviour in honey bees.Scientific reports · 2015Article
- Borna disease virus phosphoprotein impairs the developmental program controlling neurogenesis and reduces human GABAergic neurogenesis.PLoS pathogens · 2015Article
- Article
- Cytokine levels in CSF and neuropsychological performance in HIV patients.Journal of neurovirology · 2012Article
- Upregulation of insulin-like growth factor binding protein 3 in astrocytes of transgenic mice that express Borna disease virus phosphoprotein.Journal of virology · 2011Article
- Animal models of virus-induced neurobehavioral sequelae: recent advances, methodological issues, and future prospects.Interdisciplinary perspectives on infectious diseases · 2010Article
- Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity.PLoS pathogens · 2009Article
- Proteomic analysis reveals selective impediment of neuronal remodeling upon Borna disease virus infection.Journal of virology · 2008Article
- RNA from Borna disease virus in patients with schizophrenia, schizoaffective patients, and in their biological relatives.Journal of clinical laboratory analysis · 2008Article
- Virus infection causes specific learning deficits in honeybee foragers.Proceedings. Biological sciences · 2007Article
- Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling.PLoS pathogens · 2006Article
- Pathophysiology of human paralytic rabies.Journal of neurovirology · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One hypothesis for the etiology of neuropsychiatric disorders proposes that viral infection contributes to the induction of neuronal system dysfunction, resulting in a wide range of behavioral abnormalities. Recent research in molecular biology supports this hypothesis and refocuses on the role of viral infection in the development of psychiatric disorders. Viral infection can induce deleterious effects in the central nervous system by direct and/or indirect pathways. Understanding the mechanisms of glial cell dysfunction caused by persistent viral infection should lead to novel insights into the development of neurobehavioral disorders, including human mental illnesses, and to the possible development of treatments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.