ReviewJournal of autism and developmental disorders2004
Conducting genetic epidemiology studies of autism spectrum disorders: issues in matching.
Review in Journal of autism and developmental disorders, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Knowledge mapping of autistic traits: a visual analysis via CiteSpace.Frontiers in psychiatry · 2025Review
- Genetic and Environmental Epidemiology of Autism Spectrum Disorder: A Critical Gap of Interest in Global Psychiatry.Psychiatric research and clinical practice · 2025Article
- Perinatal Depression and Risk of Suicidal Behavior.JAMA network open · 2024Article
- A functional polymorphism of the brain derived neurotrophic factor gene and cortical anatomy in autism spectrum disorder.Journal of neurodevelopmental disorders · 2009Article
- Studying the emergence of autism spectrum disorders in high-risk infants: methodological and practical issues.Journal of autism and developmental disorders · 2007Article
- Stereotyped motor behaviors associated with autism in high-risk infants: a pilot videotape analysis of a sibling sample.Journal of autism and developmental disorders · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this review is to clarify the role of matching in family genetic studies of autism as a way of defining endophenotypes for linkage analysis. The concept of a confounding variable is reviewed and the importance of considering these in family studies of three endophenotypes in autism are considered: cognitive/language impairments, psychiatric disorders, and autistic-like traits. The importance of matching in infant sibling studies of autism is also addressed. Matching as a way of dealing with confounding variables has an important impact on understanding the extent to which these phenotypes are associated with the genes that confer susceptibility to autism and to the early detection of the disorder. Matching continues to be an important issue in the planning and conduct of family-genetic studies of the autism spectrum disorders, particularly as the search for autism susceptibility genes enters the next generation of studies.
Indexed as
Identifiers
15098957What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.