ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
The classical receptive field surround of primate parasol ganglion cells is mediated primarily by a non-GABAergic pathway.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed, 121 citations in OpenAlex.
- Origin and functional impact of early nonlinearities in primate retina.bioRxiv : the preprint server for biology · 2026Article
- Review
- Neural encoding with unsupervised spiking convolutional neural network.Communications biology · 2023Article
- Diversity of Ganglion Cell Responses to Saccade-Like Image Shifts in the Primate Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Origins of direction selectivity in the primate retina.Nature communications · 2022Article
- Synchronous inhibitory pathways create both efficiency and diversity in the retina.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Wide-field amacrine cell inputs to ON parasol ganglion cells in macaque retina.The Journal of comparative neurology · 2020Article
- Dopaminergic Modulation of Signal Processing in a Subset of Retinal Bipolar Cells.Frontiers in cellular neuroscience · 2020Article
- Connectomic Identification and Three-Dimensional Color Tuning of S-OFF Midget Ganglion Cells in the Primate Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Diverse Cell Types, Circuits, and Mechanisms for Color Vision in the Vertebrate Retina.Physiological reviews · 2019Review
- Article
- Nonselective Wiring Accounts for Red-Green Opponency in Midget Ganglion Cells of the Primate Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Spatiotemporal characteristics of retinal response to network-mediated photovoltaic stimulation.Journal of neurophysiology · 2018Article
- Article
- The impact of inhibitory mechanisms in the inner retina on spatial tuning of RGCs.Scientific reports · 2016Article
- Retinal Lateral Inhibition Provides the Biological Basis of Long-Range Spatial Induction.PloS one · 2016Article
- Mapping nonlinear receptive field structure in primate retina at single cone resolution.eLife · 2015Article
- The Synaptic and Morphological Basis of Orientation Selectivity in a Polyaxonal Amacrine Cell of the Rabbit Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Article
- GABAergic neurotransmission and retinal ganglion cell function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Although the center-surround receptive field is a fundamental property of retinal ganglion cells, the circuitry that mediates surround inhibition remains controversial. We examined the contribution of horizontal cells and amacrine cells to the surround of parasol ganglion cells of macaque and baboon retina by measuring receptive field structure before and during the application of drugs that have been shown previously to affect surrounds in a range of mammalian and nonmammalian species. Carbenoxolone and cobalt, thought to attenuate feedback from horizontal cells to cones, severely reduced the surround. Tetrodotoxin, which blocks sodium spiking in amacrine cells, and picrotoxin, which blocks the inhibitory action of GABA, only slightly reduced the surround. These data are consistent with the hypothesis that the surrounds of light-adapted parasol ganglion cells are generated primarily by non-GABAergic horizontal cell feedback in the outer retina, with a small contribution from GABAergic amacrine cells of the inner retina.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.