ReviewClinical microbiology reviews2004
Foot-and-mouth disease.
Review in Clinical microbiology reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 638 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
638 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,804 citations in OpenAlex.
- A systematic review of epidemiological modelling in response to lumpy skin disease outbreaks.Frontiers in veterinary science · 2024Pooled it
- Buffaloed in Brandenburg: Germany's first brush with foot-and-mouth disease after four decades of freedom.Science advances · 2026Article
- Article
- Article
- Novel Thermostabilizing Formulation for Enhanced Stability of Foot-and-Mouth Disease Virus During Storage and Environmental Stress.Microorganisms · 2026Article
- Virus-Dependent Relative Contributions of Citric Acid and Benzalkonium Chloride to the Virucidal Efficacy of Combination Disinfectants.Microorganisms · 2026Article
- Research Progress on the Major Histocompatibility Complex in Herbivores: Structure, Genetics, and Disease Resistance.Biology · 2026Review
- Redox cycling of viral RNA polymerase controls picornavirus replication.Nature communications · 2026Article
- Development of a Competitive Chemiluminescent Enzyme Immunoassay Based on Recombinant FMDV VP2 Protein for Rapid and Simultaneous Detection of Antibodies Against Foot-and-Mouth Disease Virus Serotypes O and A.Veterinary sciences · 2026Article
- Differential effects of foot-and-mouth disease infection and vaccination on fertility of Holstein-Friesian heifers: Evidence from a within-animal retrospective study in Indonesia.Veterinary world · 2026Article
- Attenuation without protective immunogenicity: effects of codon-pair deoptimization on foot-and-mouth disease virus serotype O in swine.Scientific reports · 2026Article
- Assessing the effects of limited vaccine supply on risk-based vaccination strategies in regions of endemic foot-and-mouth disease.Veterinary research · 2026Article
- Serotype Characterization and Transmission Modelling of Foot-and-Mouth Disease in Dairy Farms, Bishoftu, Ethiopia.Veterinary medicine and science · 2026Article
- Isolation and molecular characterization of foot-and-mouth disease viruses from small ruminants in Nigeria.Veterinary research · 2026Article
- Spatiotemporal trends of foot and mouth disease (FMD) in Bangladesh from 2017 to 2023 and their associations with climatic factors and machine learning (ML) based prediction.Scientific reports · 2026Article
- Emergence of foot-and-mouth disease virus SAT 1 topotype III in Iran: molecular and phylogenetic analysis.Virus genes · 2026Article
- Interactions between the 2C protein of foot-and-mouth disease virus and components of the viral replication machinery are mediated by endoplasmic reticulum-derived membranes.The Journal of general virology · 2026Article
- Article
- LC3-associated phagocytosis is a new strategy to inhibit picornavirus infection through increasing interferon levels and lysosomal degradation.Cellular and molecular life sciences : CMLS · 2026Article
- Estimation of seroconversion and vaccination impact against FMD in India during 2006-2022 using survey sampling and Bayesian approaches.Scientific reports · 2026Article
578 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. The disease was initially described in the 16th century and was the first animal pathogen identified as a virus. Recent FMD outbreaks in developed countries and their significant economic impact have increased the concern of governments worldwide. This review describes the reemergence of FMD in developed countries that had been disease free for many years and the effect that this has had on disease control strategies. The etiologic agent, FMD virus (FMDV), a member of the Picornaviridae family, is examined in detail at the genetic, structural, and biochemical levels and in terms of its antigenic diversity. The virus replication cycle, including virus-receptor interactions as well as unique aspects of virus translation and shutoff of host macromolecular synthesis, is discussed. This information has been the basis for the development of improved protocols to rapidly identify disease outbreaks, to differentiate vaccinated from infected animals, and to begin to identify and test novel vaccine candidates. Furthermore, this knowledge, coupled with the ability to manipulate FMDV genomes at the molecular level, has provided the framework for examination of disease pathogenesis and the development of a more complete understanding of the virus and host factors involved.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.