ArticleGenetics2004
Do quantitative trait loci (QTL) for a courtship song difference between Drosophila simulans and D. sechellia coincide with candidate genes and intraspecific QTL?
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 96 citations in OpenAlex.
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- Two major-effect loci influence interspecific mating in females of the sibling species, Drosophila simulans and D. sechellia.G3 (Bethesda, Md.) · 2025Article
- Genomics of a sexually selected sperm ornament and female preference in Drosophila.Nature ecology & evolution · 2025Article
- Testing the genomic overlap between intraspecific mating traits and interspecific mating barriers.Evolution letters · 2024Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
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- Behavioral Evolution ofGenes · 2020Review
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- The Role of Transposable Elements in Speciation.Genes · 2018Review
- Optogenetic Activation of theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Moving Speciation Genetics Forward: Modern Techniques Build on Foundational Studies inGenetics · 2017Review
- Genetic and Transgenic Reagents forG3 (Bethesda, Md.) · 2017Article
- Genetic basis of allochronic differentiation in the fall armyworm.BMC evolutionary biology · 2017Article
- Genetic dissection of intraspecific variation in a male-specific sexual trait in Drosophila melanogaster.Heredity · 2016Article
- Quantitative Trait Locus Analysis of Mating Behavior and Male Sex Pheromones in Nasonia Wasps.G3 (Bethesda, Md.) · 2016Article
- Heritable variation in courtship patterns in Drosophila melanogaster.G3 (Bethesda, Md.) · 2015Article
- Article
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2 authors.
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Abstract
The genetic architecture of traits influencing sexual isolation can give insight into the evolution of reproductive isolation and hence speciation. Here we report a quantitative trait loci (QTL) analysis of the difference in mean interpulse interval (IPI), an important component of the male courtship song, between Drosophila simulans and D. sechellia. Using a backcross analysis, we find six QTL that explain a total of 40.7% of the phenotypic variance. Three candidate genes are located in the intervals bounded by two of the QTL and there are no significant QTL on the X chromosome. The values of mean IPI for hybrid individuals imply the presence of dominant alleles or epistasis. Because unisexual hybrid sterility prevents an F(2) analysis, we cannot distinguish dominant from additive genetic effects at the scale of QTL. A comparison with a study of QTL for intraspecific variation in D. melanogaster shows that, for these strains, the QTL we have identified for interspecific variation cannot be those that contribute to intraspecific variation. We find that the QTL have bidirectional effects, which indicates that the genetic architecture is compatible with divergence due to genetic drift, although other possibilities are discussed.
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