ArticleJournal of virology2004
Delivery of short hairpin RNA sequences by using a replication-competent avian retroviral vector.
Article in Journal of virology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
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- AKT1Molecular cancer research : MCR · 2019Article
- New α- and SIN γ-retrovectors for safe transduction and specific transgene expression in pancreatic β cell lines.BMC biotechnology · 2019Article
- Resistance mechanisms to genetic suppression of mutant NRAS in melanoma.Melanoma research · 2017Article
- Identification and Characterization of Metastatic Factors by Gene Transfer into the Novel RIP-Tag; RIP-tva Murine Model.Journal of visualized experiments : JoVE · 2017Article
- Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.Oncogene · 2017Article
- Accelerating cancer modeling with RNAi and nongermline genetically engineered mouse models.Cold Spring Harbor protocols · 2013Review
- Rediscovering the chick embryo as a model to study retinal development.Neural development · 2012Review
- Production of avian retroviruses and tissue-specific somatic retroviral gene transfer in vivo using the RCAS/TVA system.Nature protocols · 2012Article
- WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.Neurosurgery · 2012Article
- Animal models of melanoma: a somatic cell gene delivery mouse model allows rapid evaluation of genes implicated in human melanoma.Chinese journal of cancer · 2011Review
- Akt signaling is required for glioblastoma maintenance in vivo.American journal of cancer research · 2011Article
- Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice.Pigment cell & melanoma research · 2010Article
- Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Oncogene · 2010Article
- Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.Cell communication and signaling : CCS · 2009Article
- A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome.Retrovirology · 2007Article
- Reconstituted influenza virus envelopes as an efficient carrier system for cellular delivery of small-interfering RNAs.Gene therapy · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While recent studies have demonstrated that retroviral vectors can be used to stably express short hairpin RNA (shRNA) to inhibit gene expression, these studies have utilized replication-defective retroviruses. We describe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressing shRNA that inhibits the expression of specific genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.