ArticleEmerging infectious diseases2004
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from pigs to humans, Taiwan.
Article in Emerging infectious diseases, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- Systematic review: genotypic and phenotypic resistance of fluoroquinolone-resistantFrontiers in veterinary science · 2025Pooled it
- Detection of Campylobacter jejuni and Salmonella typhimurium in chicken using PCR for virulence factor hipO and invA genes (Saudi Arabia).Bioscience reports · 2021Article
- Mucosal IgA and IFN-γScientific reports · 2017Article
- Current Perspectives on Viable but Non-culturable State in Foodborne Pathogens.Frontiers in microbiology · 2017Review
- Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidalAntimicrobial resistance and infection control · 2017Article
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- Trends in serotype distribution and antimicrobial susceptibility in Salmonella enterica isolates from humans in Belgium, 2009 to 2013.Antimicrobial agents and chemotherapy · 2015Article
- Decline of Salmonella enterica serotype Choleraesuis infections, Taiwan.Emerging infectious diseases · 2014Article
- Polymorphism of gene cassette promoter variants of class 1 integron harbored in S. Choleraesuis and Typhimurium isolated from Taiwan.BioMedicine · 2014Article
- Isolation and characterization of Salmonella enterica in day-old ducklings in Egypt.Pathogens and global health · 2014Article
- Azithromycin and ciprofloxacin resistance in Salmonella bloodstream infections in Cambodian adults.PLoS neglected tropical diseases · 2012Article
- beta-Lactam resistance in salmonella strains isolated from retail meats in the United States by the National Antimicrobial Resistance Monitoring System between 2002 and 2006.Applied and environmental microbiology · 2009Article
- Drug-resistant nontyphoidal Salmonella bacteremia, Thailand.Emerging infectious diseases · 2007Article
- Bacteraemia due to ciprofloxacin-resistant Salmonella enterica serotype Choleraesuis in adult patients at a university hospital in Taiwan, 1996-2004.Epidemiology and infection · 2006Article
- Ciprofloxacin-resistant Salmonella Kentucky in travelers.Emerging infectious diseases · 2006Article
- Antimicrobial susceptibility and characterization of Salmonella isolates from processed bison carcasses.Applied and environmental microbiology · 2006Article
- Multidrug resistance in Salmonella enterica serotype Typhimurium from humans in France (1993 to 2003).Journal of clinical microbiology · 2006Article
- Fluoroquinolone-resistant Salmonella sp. in carcasses.Emerging infectious diseases · 2006Article
- Novel attenuated Salmonella enterica serovar Choleraesuis strains as live vaccine candidates generated by signature-tagged mutagenesis.Infection and immunity · 2005Article
- Characterization of isolates of Salmonella enterica serovar typhimurium displaying high-level fluoroquinolone resistance in Japan.Journal of clinical microbiology · 2005Article
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23 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated the disk susceptibility data of 671 nontyphoid Salmonella isolates collected from different parts of Taiwan from March 2001 to August 2001 and 1,261 nontyphoid Salmonella isolates from the National Taiwan University Hospital from 1996 to 2001. Overall, ciprofloxacin resistance was found in 2.7% (18/671) of all nontyphoid Salmonella isolates, in 1.4% (5/347) of Salmonella enterica serotype Typhimurium and in 7.5% (8/107) in S. enterica serotype Choleraesuis nationwide. MICs of six newer fluoroquinolones were determined for the following isolates: 37 isolates of ciprofloxacin-resistant (human) S. Typhimurium (N = 26) and Choleraesuis (N = 11), 10 isolates of ciprofloxacin-susceptible (MIC <1 mg/mL) (human) isolates of these two serotypes, and 15 swine isolates from S. Choleraesuis (N = 13) and Typhmurium (N = 2) with reduced susceptibility to ciprofloxacin (MIC >0.12 microg/mL). Sequence analysis of the gryA, gyrB, parC, parE, and acrR genes, ciprofloxacin accumulation, and genotypes generated by pulsed-field gel electrophoresis with three restriction enzymes (SpeI, XbaI, and BlnI) were performed. All 26 S. Typhimurium isolates from humans and pigs belonged to genotype I. For S. Choleraesuis isolates, 91% (10/11) of human isolates and 54% (7/13) of swine isolates belonged to genotype B. These two genotypes isolates from humans all exhibited a high-level of resistance to ciprofloxacin (MIC 16-64 mg/mL). They had two-base substitutions in the gyrA gene at codons 83 (Ser83Phe) and 87 (Asp87Gly or Asp87Asn) and in the parC gene at codon 80 (Ser80Arg, Ser80Ile, or Ser84Lys). Our investigation documented that not only did these two S. enterica isolates have a high prevalence of ciprofloxacin resistance nationwide but also that some closely related ciprofloxacin-resistant strains are disseminated from pigs to humans.
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