Evidence map›Paper›PMID 15075263›Full record

ArticleEukaryotic cell2004

Translational accuracy during exponential, postdiauxic, and stationary growth phases in Saccharomyces cerevisiae.

Guillaume Stahl, Samia N Ben Salem, Lifeng Chen, Bing Zhao, Philip J Farabaugh

Open access · diamondAbstract read
In one paragraph

Article in Eukaryotic cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 54 citations in OpenAlex.

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  9. Bioremediation of Wastewater Using Yeast Strains: An Assessment of Contaminant Removal Efficiency.International journal of environmental research and public health · 2023
    Article
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  12. Sound Stimulation Can AffectMetabolites · 2021
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  13. The bubble-induced population dynamics of fermenting yeasts.Journal of the Royal Society, Interface · 2020
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  17. Review
  18. Filamentation of Metabolic Enzymes in Saccharomyces cerevisiae.Journal of genetics and genomics = Yi chuan xue bao · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Guillaume StahlDepartment of Biological Sciences, University of Maryland Baltimore County, Baltimore, Maryland 21250, USA. stahl@infobiogen.fr
Samia N Ben Salem
Lifeng Chen
Bing Zhao
Philip J Farabaugh
University of Maryland, Baltimore County · US

Funding

The genetics of ribosomal reading frame maintenanceR01GM029480 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI FARABAUGH, PHILIP JAMES · 1985 to 2010
$2.7M
Molecular genetics of translational accuracyR56GM029480 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI FARABAUGH, PHILIP JAMES · 2007 to 2007
$323k
NIGMS NIH HHS GM29480NIGMS NIH HHS R01 GM029480NIGMS NIH HHS R56 GM029480
6 · The paper itself

Abstract

When the yeast Saccharomyces cerevisiae shifts from rapid growth on glucose to slow growth on ethanol, it undergoes profound changes in cellular metabolism, including the destruction of most of the translational machinery. We have examined the effect of this metabolic change, termed the diauxic shift, on the frequency of translational errors. Recoding sites are mRNA sequences that increase the frequency of translational errors, providing a convenient reporter of translational accuracy. We found that the diauxic shift causes no overall change in translational accuracy but does cause a strong reduction in the frequency of one type of programmed error: Ty +1 frameshifting. Genetic data suggest that this effect may be due to changes in the relative amounts of tRNA participating in translation elongation. We discuss possible implications for expression strategies that use recoding.

Indexed as

Protein BiosynthesisCodonEthanolFrameshifting, RibosomalGlucoseRetroelementsRNA, Transfer, Amino AcylSaccharomyces cerevisiaeCodonEthanolGlucoseRetroelementsRNA, Transfer, Amino Acyl

Identifiers

PMID15075263
PMCPMC387642
OpenAlexW2154321158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.