Efficacy and safety of antidepressants for children and adolescents.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

53 citing papers in PubMed, 5 syntheses or guidelines pooled it.

1. New generation antidepressants for depression in children and adolescents: a network meta-analysis.The Cochrane database of systematic reviews · 2021
   Pooled it
2. Effectiveness and side effects of psychopharmacotherapy in individuals with 22q11.2 deletion syndrome with comorbid psychiatric disorders: a systematic review.European child & adolescent psychiatry · 2020
   Pooled it
3. Newer generation antidepressants for depressive disorders in children and adolescents.The Cochrane database of systematic reviews · 2012
   Pooled it
4. Are child and adolescent responses to placebo higher in major depression than in anxiety disorders? A systematic review of placebo-controlled trials.PloS one · 2008
   Pooled it
5. Is there evidence for negative effects of antidepressants on suicidality in depressive patients? A systematic review.European archives of psychiatry and clinical neuroscience · 2006
   Pooled it
6. Evaluation of the efficacy and safety of olanzapine as an adjunctive treatment for anorexia nervosa in adolescent females: a randomized, double-blind, placebo-controlled trial.BMC pediatrics · 2008
   Trial
7. fMRI predictors of treatment outcome in pediatric anxiety disorders.Psychopharmacology · 2007
   Trial
8. Commentary: Industry collaboration: A call for 'industry literacy' - a commentary on Bourgaize et al. (2025).Child and adolescent mental health · 2025
   Article
9. Treatment resistant psychosis in children and adolescents and clozapine: Nuances.Frontiers in psychiatry · 2023
   Review
10. Integrative multi-omics landscape of fluoxetine action across 27 brain regions reveals global increase in energy metabolism and region-specific chromatin remodelling.Molecular psychiatry · 2022
    Article
11. Surgery to relieve nasal obstruction: outcome for 366 patients operated on by one senior surgeon.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
12. Pharmacological Approaches to Managing Violence and Aggression in Prison Populations: Clinical and Ethical Issues.Drugs · 2020
    Review
13. Editorial: Antidepressant Prescriptions in Children and Adolescents.Frontiers in psychiatry · 2020
    Article
14. Comparative efficacy and acceptability of psychotherapies for depression in children and adolescents: A systematic review and network meta-analysis.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2015
    Article
15. Effects of chronic fluoxetine treatment on neurogenesis and tryptophan hydroxylase expression in adolescent and adult rats.PloS one · 2014
    Article
16. Magnetic seizure therapy in an adolescent with refractory bipolar depression: a case report.Neuropsychiatric disease and treatment · 2014
    Article
17. Increased response to a 5-HT challenge after discontinuation of chronic serotonin uptake inhibition in the adult and adolescent rat brain.PloS one · 2014
    Article
18. Making decisions about treatment for young people diagnosed with depressive disorders: a qualitative study of clinicians' experiences.BMC psychiatry · 2013
    Article
19. Addressing risks to advance mental health research.JAMA psychiatry · 2013
    Article
20. Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats.Biological psychiatry · 2013
    Article

Corrections and comments

• Erratum issued

Authors and funding

6 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as