ArticleJournal of translational medicine2004
T-cell clonotypes in cancer.
Article in Journal of translational medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Evaluating the Potential of T Cell Receptor Repertoires in Predicting the Prognosis of Resectable Non-Small Cell Lung Cancers.Molecular therapy. Methods & clinical development · 2020Article
- Immune monitoring and TCR sequencing of CD4 T cells in a long term responsive patient with metastasized pancreatic ductal carcinoma treated with individualized, neoepitope-derived multipeptide vaccines: a case report.Journal of translational medicine · 2018Article
- Analysis of T cell receptor repertoire based on Vβ chain in patients with breast cancer.Cancer biomarkers : section A of Disease markers · 2018Article
- Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer.Oncology letters · 2016Article
- Diversity index of mucosal resident T lymphocyte repertoire predicts clinical prognosis in gastric cancer.Oncoimmunology · 2015Article
- Article
- Clonal expansion of renal cell carcinoma-infiltrating T lymphocytes.Oncoimmunology · 2013Article
- Effector CD4 and CD8 T cells and their role in the tumor microenvironment.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2013Article
- The rationale of vectored gene-fusion vaccines against cancer: evolving strategies and latest evidence.Therapeutic advances in vaccines · 2013Article
- Determinants of public T cell responses.Cell research · 2012Review
- Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients.Journal of translational medicine · 2010Article
- Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients.Journal of translational medicine · 2009Article
- Relative quantification of TCR Vbeta-chain families by real time PCR for identification of clonal T-cell populations.Journal of translational medicine · 2008Article
- Article
- Understanding the response to immunotherapy in humans.Springer seminars in immunopathology · 2005Review
- Overview of melanoma vaccines and promising approaches.Current oncology reports · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cells of the immune system spontaneously recognize autologous tumor cells and T cells are believed to be the main effector cells for the immune surveillance of cancer. Recent advances in our understanding of basic and tumor immunology together with methodological developments implies that tumor specific T cells can now be studied functionally, phenotypically as well as molecularly. T cells recognize peptide antigens in the context of MHC molecules through the clonally distributed T-cell receptor (TCR), thus, the clonal distribution of the TCR offers the means to detect and track specific T cells based upon detection of the unique TCR. In this review, we present and discuss available data on TCR utilization of tumor specific T cells in murine models as well as spontaneous and treatment induced anti-tumor T-cell responses in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.