Evidence map›Paper›PMID 15072261›Full record

ReviewCerebellum (London, England)2004

Neurotrophic effects of AMPA.

Cristina Limatola

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cerebellum (London, England), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Cristina LimatolaDipartimento di Fisiologia Umana e Farmacologia, Università di Roma La Sapienza, Rome, Italy. cristina.limatola@uniroma1.it

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AMPA-type glutamate receptors may transduce both neurotoxic and neurotrophic signals, basically depending on receptor subunit composition and on the extent of receptor activation. While a great deal of data are available on the mechanisms underlying the neurotoxic effects induced by AMPA receptor stimulation, much less is known about the molecular mechanisms responsible for their neurotrophic activities. This review describes the experimental evidences in favor of a neurotrophic effect of AMPA and compares the mechanisms identified and the signaling pathways involved with those relevant for the neurotrophic activities of other neurotrophins.

Indexed as

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsCerebellumHumansNerve Growth FactorsReceptors, AMPASignal Transductionalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidNerve Growth FactorsReceptors, AMPA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.