Evidence map›Paper›PMID 15071063›Full record

ArticleJournal of clinical microbiology2004

Genotyping and antifungal susceptibility profile of Dipodascus capitatus isolates causing disseminated infection in seven hematological patients of a tertiary hospital.

Ignacio Gadea, Manuel Cuenca-Estrella, Elena Prieto, Teresa M Diaz-Guerra, Jose I Garcia-Cia, Emilia Mellado, Jose F Tomas, Juan L Rodriguez-Tudela

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. International journal of environmental research and public health · 2021
    Pooled it
  2. Medical mycology case reports · 2025
    Article
  3. Geotrichosis: fungemia in a patient with acute lymphoblastic leukemiaBiomedica : revista del Instituto Nacional de Salud · 2023
    Article
  4. Invasive Fungal Infection Caused byJournal of fungi (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
  7. Outbreak ofFrontiers in microbiology · 2020
    Article
  8. Article
  9. Frontiers in microbiology · 2019
    Article
  10. First case of invasiveMedical mycology case reports · 2017
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. A Case ofJournal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ignacio GadeaDepartamento de Microbiología, Madrid, Spain.
Manuel Cuenca-Estrella
Elena Prieto
Teresa M Diaz-Guerra
Jose I Garcia-Cia
Emilia Mellado
Jose F Tomas
Juan L Rodriguez-Tudela

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seven cases of disseminated infection due to Dipodascus capitatus are reported. Infections occurred in a hematological unit of a tertiary hospital during a period of 5 years. Five cases were refractory to antifungal therapy. Antifungal susceptibility testing of seven isolates was performed, and strains were typed by PCR fingerprinting with the core sequence of phage M13 and by random amplification of polymorphic DNA with two primers, Ap12h and W-80A. A very short range of MICs of each antifungal agent was observed. The MICs of amphotericin B ranged between 0.50 and 2 microg/ml. Strains were susceptible in vitro to flucytosine and susceptible (dose-dependent) to fluconazole and itraconazole. Voriconazole exhibited an activity in vitro comparable to that of itraconazole. Typing techniques allowed seven additional isolates of D. capitatus neither geographically nor temporally related to be classified into two different genomic patterns. The genomic type of the seven strains from the hematological unit was identical regardless of typing technique utilized. It would indicate that the seven cases of disseminated infection could be related epidemiologically.

Indexed as

AdultAgedAntifungal AgentsCerebrospinal FluidDNA FingerprintingFemaleFungemiaGenotypeHospitalsHumansLeukemiaMaleMicrobial Sensitivity TestsMiddle AgedMycological Typing TechniquesMycosesAntifungal Agents

Identifiers

PMID15071063
PMCPMC387620

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.